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The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users.
Shram MJ, Henningfield JE, Apseloff G, Gorodetzky CW, De Martin S, Vocci FL, Sapienza FL, Kosten TR, Huston J, Buchhalter A, Ashworth J, Lanier R, Folli F, Mattarei A, Guidetti C, Comai S, O'Gorman C, Traversa S, Inturrisi CE, Manfredi PL, Pappagallo M. Shram MJ, et al. Among authors: de martin s. Transl Psychiatry. 2023 Jun 7;13(1):192. doi: 10.1038/s41398-023-02473-8. Transl Psychiatry. 2023. PMID: 37286536 Free PMC article. Clinical Trial.
The Extra Virgin Olive Oil Polyphenol Oleocanthal Exerts Antifibrotic Effects in the Liver.
Gabbia D, Carpi S, Sarcognato S, Cannella L, Colognesi M, Scaffidi M, Polini B, Digiacomo M, Esposito Salsano J, Manera C, Macchia M, Nieri P, Carrara M, Russo FP, Guido M, De Martin S. Gabbia D, et al. Among authors: de martin s. Front Nutr. 2021 Oct 4;8:715183. doi: 10.3389/fnut.2021.715183. eCollection 2021. Front Nutr. 2021. PMID: 34671630 Free PMC article.
Primary biliary cholangitis: perception and expectation of illness.
Floreani A, Scaffidi M, Coco B, Giannini EG, Labanca S, Bonaiuto E, De Martin S, Invernizzi P, Carbone M, Alvaro D, Bragazzi MC, Calvaruso V, Cossiga V, Cazzagon N; Italian Foundation for Research in Hepatology (FIRE). Floreani A, et al. Among authors: de martin s. Dig Liver Dis. 2022 Sep;54(9):1230-1233. doi: 10.1016/j.dld.2022.02.006. Epub 2022 Mar 8. Dig Liver Dis. 2022. PMID: 35277351
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma.
Infante P, Malfanti A, Quaglio D, Balducci S, De Martin S, Bufalieri F, Mastrotto F, Basili I, Garofalo M, Lospinoso Severini L, Mori M, Manni I, Moretti M, Nicoletti C, Piaggio G, Caliceti P, Botta B, Ghirga F, Salmaso S, Di Marcotullio L. Infante P, et al. Among authors: de martin s. Cancer Lett. 2021 Feb 28;499:220-231. doi: 10.1016/j.canlet.2020.11.028. Epub 2020 Nov 26. Cancer Lett. 2021. PMID: 33249196 Free article.
Enzyme inhibition and induction in liver disease.
Palatini P, De Martin S, Pegoraro P, Orlando R. Palatini P, et al. Among authors: de martin s. Curr Clin Pharmacol. 2008 Jan;3(1):56-69. doi: 10.2174/157488408783329896. Curr Clin Pharmacol. 2008. PMID: 18690879 Review.
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs.
Gabbia D, Carpi S, Sarcognato S, Zanotto I, Sayaf K, Colognesi M, Polini B, Digiacomo M, Macchia M, Nieri P, Carrara M, Cazzagon N, Russo FP, Guido M, De Martin S. Gabbia D, et al. Among authors: de martin s. Biomed Pharmacother. 2023 Jan;157:114014. doi: 10.1016/j.biopha.2022.114014. Epub 2022 Nov 12. Biomed Pharmacother. 2023. PMID: 36379119 Free article.
104 results