Eissa IH - Search Results

1

Design, synthesis, docking, MD simulations, and anti-proliferative evaluation of thieno[2,3-d]pyrimidine derivatives as new EGFR inhibitors.

Sobh EA, Dahab MA, Elkaeed EB, Alsfouk AA, Ibrahim IM, Metwaly AM, Eissa IH. Sobh EA, et al. Among authors: eissa ih. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2220579. doi: 10.1080/14756366.2023.2220579. J Enzyme Inhib Med Chem. 2023. PMID: 37288786 Free PMC article.

2

Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPARγ and SUR agonists.

Ibrahim MK, Eissa IH, Abdallah AE, Metwaly AM, Radwan MM, ElSohly MA. Ibrahim MK, et al. Among authors: eissa ih. Bioorg Med Chem. 2017 Feb 15;25(4):1496-1513. doi: 10.1016/j.bmc.2017.01.015. Epub 2017 Jan 16. Bioorg Med Chem. 2017. PMID: 28117121

3

Design and Discovery of Novel Quinoxaline Derivatives as Dual DNA Intercalators and Topoisomerase II Inhibitors.

Eissa IH, El-Naggar AM, El-Sattar NEAA, Youssef ASA. Eissa IH, et al. Anticancer Agents Med Chem. 2018;18(2):195-209. doi: 10.2174/1871520617666170710182405. Anticancer Agents Med Chem. 2018. PMID: 28699490

4

Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of quinazolin-4(3H)-one derivatives as potential PPARγ and SUR agonists.

Ibrahim MK, Eissa IH, Alesawy MS, Metwaly AM, Radwan MM, ElSohly MA. Ibrahim MK, et al. Among authors: eissa ih. Bioorg Med Chem. 2017 Sep 1;25(17):4723-4744. doi: 10.1016/j.bmc.2017.07.015. Epub 2017 Jul 8. Bioorg Med Chem. 2017. PMID: 28720328

5

Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.

Ibrahim MK, Taghour MS, Metwaly AM, Belal A, Mehany ABM, Elhendawy MA, Radwan MM, Yassin AM, El-Deeb NM, Hafez EE, ElSohly MA, Eissa IH. Ibrahim MK, et al. Among authors: eissa ih. Eur J Med Chem. 2018 Jul 15;155:117-134. doi: 10.1016/j.ejmech.2018.06.004. Epub 2018 Jun 4. Eur J Med Chem. 2018. PMID: 29885574

6

Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFR^WT and EGFR^T790M inhibitors and apoptosis inducers.

Gaber AA, Bayoumi AH, El-Morsy AM, Sherbiny FF, Mehany ABM, Eissa IH. Gaber AA, et al. Among authors: eissa ih. Bioorg Chem. 2018 Oct;80:375-395. doi: 10.1016/j.bioorg.2018.06.017. Epub 2018 Jun 12. Bioorg Chem. 2018. PMID: 29986185

7

Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.

Elmetwally SA, Saied KF, Eissa IH, Elkaeed EB. Elmetwally SA, et al. Among authors: eissa ih. Bioorg Chem. 2019 Jul;88:102944. doi: 10.1016/j.bioorg.2019.102944. Epub 2019 Apr 25. Bioorg Chem. 2019. PMID: 31051400

8

Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.

Eissa IH, Metwaly AM, Belal A, Mehany ABM, Ayyad RR, El-Adl K, Mahdy HA, Taghour MS, El-Gamal KMA, El-Sawah ME, Elmetwally SA, Elhendawy MA, Radwan MM, ElSohly MA. Eissa IH, et al. Arch Pharm (Weinheim). 2019 Nov;352(11):e1900123. doi: 10.1002/ardp.201900123. Epub 2019 Aug 29. Arch Pharm (Weinheim). 2019. PMID: 31463953

9

Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4(3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers.

Mahdy HA, Ibrahim MK, Metwaly AM, Belal A, Mehany ABM, El-Gamal KMA, El-Sharkawy A, Elhendawy MA, Radwan MM, Elsohly MA, Eissa IH. Mahdy HA, et al. Among authors: eissa ih. Bioorg Chem. 2020 Jan;94:103422. doi: 10.1016/j.bioorg.2019.103422. Epub 2019 Nov 12. Bioorg Chem. 2020. PMID: 31812261

10

Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors.

El-Helby AA, Sakr H, Ayyad RR, Mahdy HA, Khalifa MM, Belal A, Rashed M, El-Sharkawy A, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Eissa IH. El-Helby AA, et al. Among authors: eissa ih. Bioorg Chem. 2020 Oct;103:104233. doi: 10.1016/j.bioorg.2020.104233. Epub 2020 Aug 26. Bioorg Chem. 2020. PMID: 32882440

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