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Syk Inhibition Reprograms Tumor-Associated Macrophages and Overcomes Gemcitabine-Induced Immunosuppression in Pancreatic Ductal Adenocarcinoma.
Rohila D, Park IH, Pham TV, Weitz J, Hurtado de Mendoza T, Madheswaran S, Ishfaq M, Beaman C, Tapia E, Sun S, Patel J, Tamayo P, Lowy AM, Joshi S. Rohila D, et al. Among authors: lowy am. Cancer Res. 2023 Aug 15;83(16):2675-2689. doi: 10.1158/0008-5472.CAN-22-3645. Cancer Res. 2023. PMID: 37306759 Free PMC article.
Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis.
Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. Garmy-Susini B, et al. Cancer Res. 2010 Apr 15;70(8):3042-51. doi: 10.1158/0008-5472.CAN-09-3761. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388801 Free PMC article.
A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer.
Fujimura K, Wright T, Strnadel J, Kaushal S, Metildi C, Lowy AM, Bouvet M, Kelber JA, Klemke RL. Fujimura K, et al. Among authors: lowy am. Cancer Res. 2014 Nov 15;74(22):6671-81. doi: 10.1158/0008-5472.CAN-14-1031. Epub 2014 Sep 26. Cancer Res. 2014. PMID: 25261239 Free PMC article.
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Kaneda MM, Cappello P, Nguyen AV, Ralainirina N, Hardamon CR, Foubert P, Schmid MC, Sun P, Mose E, Bouvet M, Lowy AM, Valasek MA, Sasik R, Novelli F, Hirsch E, Varner JA. Kaneda MM, et al. Among authors: lowy am. Cancer Discov. 2016 Aug;6(8):870-85. doi: 10.1158/2159-8290.CD-15-1346. Epub 2016 May 13. Cancer Discov. 2016. PMID: 27179037 Free PMC article.
Tumor-penetrating therapy for β5 integrin-rich pancreas cancer.
Hurtado de Mendoza T, Mose ES, Botta GP, Braun GB, Kotamraju VR, French RP, Suzuki K, Miyamura N, Teesalu T, Ruoslahti E, Lowy AM, Sugahara KN. Hurtado de Mendoza T, et al. Among authors: lowy am. Nat Commun. 2021 Mar 9;12(1):1541. doi: 10.1038/s41467-021-21858-1. Nat Commun. 2021. PMID: 33750829 Free PMC article.
241 results