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Multi-chemokine receptor antagonist RAP-103 inhibits opioid-derived respiratory depression, reduces opioid reinforcement and physical dependence, and normalizes opioid-induced dysregulation of mesolimbic chemokine receptors in rats.
Bongiovanni AR, Zhao P, Inan S, Wiah S, Shekarabi A, Farkas DJ, Watson MN, Wimmer ME, Ruff MR, Rawls SM. Bongiovanni AR, et al. Among authors: inan s. Drug Alcohol Depend. 2022 Sep 1;238:109556. doi: 10.1016/j.drugalcdep.2022.109556. Epub 2022 Jul 11. Drug Alcohol Depend. 2022. PMID: 35843139 Free PMC article.
Purinergic P2X7 receptor antagonist inhibits methamphetamine-induced reward, hyperlocomotion, and cortical IL-7A levels in mice: A role for P2X7/IL-17A crosstalk in methamphetamine behaviors?
Potula R, Gentile TA, Meissler JJ, Shekarabi A, Wiah S, Farkas DJ, Inan S, Eisenstein TK, Rawls SM. Potula R, et al. Among authors: inan s. Brain Behav Immun. 2023 Jan;107:47-52. doi: 10.1016/j.bbi.2022.09.012. Epub 2022 Sep 26. Brain Behav Immun. 2023. PMID: 36174884 Free PMC article.
NCP, a dual kappa and mu opioid receptor agonist, is a potent analgesic against inflammatory pain without reinforcing or aversive properties.
Huang P, Ho CK, Cao D, Inan S, Rawls SM, Li M, Huang B, Pagare PP, Townsend EA, Poklis JL, Halquist MS, Banks M, Zhang Y, Liu-Chen LY. Huang P, et al. Among authors: inan s. J Pharmacol Exp Ther. 2024 Feb 26;389(1):106-17. doi: 10.1124/jpet.123.001870. Online ahead of print. J Pharmacol Exp Ther. 2024. PMID: 38409113 Free article.
204 results