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Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
Carlson BL, Grogan PT, Mladek AC, Schroeder MA, Kitange GJ, Decker PA, Giannini C, Wu W, Ballman KA, James CD, Sarkaria JN. Carlson BL, et al. Among authors: sarkaria jn. Int J Radiat Oncol Biol Phys. 2009 Sep 1;75(1):212-9. doi: 10.1016/j.ijrobp.2009.04.026. Int J Radiat Oncol Biol Phys. 2009. PMID: 19695438 Free PMC article.
Targeting Src family kinases inhibits bevacizumab-induced glioma cell invasion.
Huveldt D, Lewis-Tuffin LJ, Carlson BL, Schroeder MA, Rodriguez F, Giannini C, Galanis E, Sarkaria JN, Anastasiadis PZ. Huveldt D, et al. Among authors: sarkaria jn. PLoS One. 2013;8(2):e56505. doi: 10.1371/journal.pone.0056505. Epub 2013 Feb 14. PLoS One. 2013. PMID: 23457577 Free PMC article.
BET bromodomain proteins are required for glioblastoma cell proliferation.
Pastori C, Daniel M, Penas C, Volmar CH, Johnstone AL, Brothers SP, Graham RM, Allen B, Sarkaria JN, Komotar RJ, Wahlestedt C, Ayad NG. Pastori C, et al. Among authors: sarkaria jn. Epigenetics. 2014 Apr;9(4):611-20. doi: 10.4161/epi.27906. Epub 2014 Feb 19. Epigenetics. 2014. PMID: 24496381 Free PMC article.
Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts.
Gupta SK, Mladek AC, Carlson BL, Boakye-Agyeman F, Bakken KK, Kizilbash SH, Schroeder MA, Reid J, Sarkaria JN. Gupta SK, et al. Among authors: sarkaria jn. Clin Cancer Res. 2014 Jul 15;20(14):3730-41. doi: 10.1158/1078-0432.CCR-13-3446. Epub 2014 May 16. Clin Cancer Res. 2014. PMID: 24838527 Free PMC article.
Critical functions of RhoB in support of glioblastoma tumorigenesis.
Ma Y, Gong Y, Cheng Z, Loganathan S, Kao C, Sarkaria JN, Abel TW, Wang J. Ma Y, et al. Among authors: sarkaria jn. Neuro Oncol. 2015 Apr;17(4):516-25. doi: 10.1093/neuonc/nou228. Epub 2014 Sep 12. Neuro Oncol. 2015. PMID: 25216671 Free PMC article.
The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma.
Pokorny JL, Calligaris D, Gupta SK, Iyekegbe DO Jr, Mueller D, Bakken KK, Carlson BL, Schroeder MA, Evans DL, Lou Z, Decker PA, Eckel-Passow JE, Pucci V, Ma B, Shumway SD, Elmquist WF, Agar NY, Sarkaria JN. Pokorny JL, et al. Among authors: sarkaria jn. Clin Cancer Res. 2015 Apr 15;21(8):1916-24. doi: 10.1158/1078-0432.CCR-14-2588. Epub 2015 Jan 21. Clin Cancer Res. 2015. PMID: 25609063 Free PMC article.
288 results