Gollapudi SK - Search Results

1

Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients.

Nag S, Gollapudi SK, Del Rio CL, Spudich JA, McDowell R. Nag S, et al. Among authors: gollapudi sk. Sci Adv. 2023 Jul 28;9(30):eabo7622. doi: 10.1126/sciadv.abo7622. Epub 2023 Jul 28. Sci Adv. 2023. PMID: 37506209 Free article. Review.

2

[No title available]

[No authors listed] [No authors listed] PMID: 36782541

3

Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States.

Gollapudi SK, Ma W, Chakravarthy S, Combs AC, Sa N, Langer S, Irving TC, Nag S. Gollapudi SK, et al. J Mol Biol. 2021 Nov 19;433(23):167295. doi: 10.1016/j.jmb.2021.167295. Epub 2021 Oct 8. J Mol Biol. 2021. PMID: 34627791 Free PMC article.

4

Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems.

Gollapudi SK, Yu M, Gan QF, Nag S. Gollapudi SK, et al. J Biol Chem. 2021 Jan-Jun;296:100114. doi: 10.1074/jbc.RA120.016506. Epub 2020 Dec 3. J Biol Chem. 2021. PMID: 33234590 Free PMC article.

5

Developmental increase in β-MHC enhances sarcomere length-dependent activation in the myocardium.

Reda SM, Gollapudi SK, Chandra M. Reda SM, et al. Among authors: gollapudi sk. J Gen Physiol. 2019 May 6;151(5):635-644. doi: 10.1085/jgp.201812183. Epub 2019 Jan 2. J Gen Physiol. 2019. PMID: 30602626 Free PMC article.

6

Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca²⁺ Sensitivity.

Gollapudi SK, Reda SM, Chandra M. Gollapudi SK, et al. Biophys J. 2017 Aug 22;113(4):880-888. doi: 10.1016/j.bpj.2017.07.002. Biophys J. 2017. PMID: 28834724 Free PMC article.

7

L71F mutation in rat cardiac troponin T augments crossbridge recruitment and detachment dynamics against α-myosin heavy chain, but not against β-myosin heavy chain.

Reda SM, Gollapudi SK, Chandra M. Reda SM, et al. Among authors: gollapudi sk. J Muscle Res Cell Motil. 2016 Dec;37(6):215-223. doi: 10.1007/s10974-016-9460-6. Epub 2016 Dec 14. J Muscle Res Cell Motil. 2016. PMID: 27975185

8

Cardiomyopathy-related mutation (A30V) in mouse cardiac troponin T divergently alters the magnitude of stretch activation in α- and β-myosin heavy chain fibers.

Mickelson AV, Gollapudi SK, Chandra M. Mickelson AV, et al. Among authors: gollapudi sk. Am J Physiol Heart Circ Physiol. 2017 Jan 1;312(1):H141-H149. doi: 10.1152/ajpheart.00487.2016. Epub 2016 Oct 21. Am J Physiol Heart Circ Physiol. 2017. PMID: 27769999 Free PMC article.

9

Dilated Cardiomyopathy Mutation (R134W) in Mouse Cardiac Troponin T Induces Greater Contractile Deficits against α-Myosin Heavy Chain than against β-Myosin Heavy Chain.

Gollapudi SK, Chandra M. Gollapudi SK, et al. Front Physiol. 2016 Oct 4;7:443. doi: 10.3389/fphys.2016.00443. eCollection 2016. Front Physiol. 2016. PMID: 27757084 Free PMC article.

10

Interplay between the effects of a Protein Kinase C phosphomimic (T204E) and a dilated cardiomyopathy mutation (K211Δ or R206W) in rat cardiac troponin T blunts the magnitude of muscle length-mediated crossbridge recruitment against the β-myosin heavy chain background.

Michael JJ, Gollapudi SK, Chandra M. Michael JJ, et al. Among authors: gollapudi sk. J Muscle Res Cell Motil. 2016 Jun;37(3):83-93. doi: 10.1007/s10974-016-9448-2. Epub 2016 Jul 13. J Muscle Res Cell Motil. 2016. PMID: 27411801

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