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Page 1
Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk.
Li Y, Chaurasia B, Rahman MM, Kaddai V, Maschek JA, Berg JA, Wilkerson JL, Mahmassani ZS, Cox J, Wei P, Meikle PJ, Atkinson D, Wang L, Poss AM, Playdon MC, Tippetts TS, Mousa EM, Nittayaboon K, Anandh Babu PV, Drummond MJ, Clevers H, Shayman JA, Hirabayashi Y, Holland WL, Rutter J, Edgar BA, Summers SA. Li Y, et al. Among authors: holland wl. Gastroenterology. 2023 Nov;165(5):1136-1150. doi: 10.1053/j.gastro.2023.07.017. Epub 2023 Aug 2. Gastroenterology. 2023. PMID: 37541526 Free PMC article.
Ceramides and Acute Kidney Injury.
Nicholson RJ, Holland WL, Summers SA. Nicholson RJ, et al. Among authors: holland wl. Semin Nephrol. 2022 May;42(3):151281. doi: 10.1016/j.semnephrol.2022.10.007. Epub 2022 Nov 18. Semin Nephrol. 2022. PMID: 36404212 Free PMC article. Review.
Disuse-induced muscle fibrosis, cellular senescence, and senescence-associated secretory phenotype in older adults are alleviated during re-ambulation with metformin pre-treatment.
Petrocelli JJ, McKenzie AI, de Hart NMMP, Reidy PT, Mahmassani ZS, Keeble AR, Kaput KL, Wahl MP, Rondina MT, Marcus RL, Welt CK, Holland WL, Funai K, Fry CS, Drummond MJ. Petrocelli JJ, et al. Among authors: holland wl. Aging Cell. 2023 Nov;22(11):e13936. doi: 10.1111/acel.13936. Epub 2023 Jul 24. Aging Cell. 2023. PMID: 37486024 Free PMC article. Clinical Trial.
Ceramides are fuel gauges on the drive to cardiometabolic disease.
Wilkerson JL, Tatum SM, Holland WL, Summers SA. Wilkerson JL, et al. Among authors: holland wl. Physiol Rev. 2024 Jul 1;104(3):1061-1119. doi: 10.1152/physrev.00008.2023. Epub 2024 Feb 1. Physiol Rev. 2024. PMID: 38300524 Review.
Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis.
Brothwell MJ, Cao 曹国燊 G, Maschek JA, Poss AM, Peterlin AD, Wang 汪立平 L, Baker TB, Shahtout JL, Siripoksup P, Pearce QJ, Johnson JM, Finger FM, Prola A, Pellizzari SA, Hale GL, Manuel AM, Watanabe 渡邉真也 S, Miranda ER, Affolter KE, Tippetts TS, Nikolova LS, Choi 崔蘭煕 RH, Decker ST, Patil M, Catrow JL, Holland WL, Nowinski SM, Lark DS, Fisher-Wellman KH, Mimche PN, Evason KJ, Cox JE, Summers SA, Gerhart-Hines Z, Funai 船井勝彦 K. Brothwell MJ, et al. Among authors: holland wl. bioRxiv [Preprint]. 2024 Oct 10:2024.10.10.617517. doi: 10.1101/2024.10.10.617517. bioRxiv. 2024. PMID: 39416056 Free PMC article. Preprint.
Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin.
Price TR, Stapleton DS, Schueler KL, Norris MK, Parks BW, Yandell BS, Churchill GA, Holland WL, Keller MP, Attie AD. Price TR, et al. Among authors: holland wl. PLoS Genet. 2023 Jul 31;19(7):e1010713. doi: 10.1371/journal.pgen.1010713. eCollection 2023 Jul. PLoS Genet. 2023. PMID: 37523383 Free PMC article.
121 results