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Page 1
Peroxisome disruption alters lipid metabolism and potentiates antitumor response with MAPK-targeted therapy in melanoma.
Huang F, Cai F, Dahabieh MS, Gunawardena K, Talebi A, Dehairs J, El-Turk F, Park JY, Li M, Goncalves C, Gagnon N, Su J, LaPierre JH, Gaub P, Joyal JS, Mitchell JJ, Swinnen JV, Miller WH Jr, Del Rincón SV. Huang F, et al. Among authors: gagnon n. J Clin Invest. 2023 Oct 16;133(20):e166644. doi: 10.1172/JCI166644. J Clin Invest. 2023. PMID: 37616051 Free PMC article.
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.
Huang F, Gonçalves C, Bartish M, Rémy-Sarrazin J, Issa ME, Cordeiro B, Guo Q, Emond A, Attias M, Yang W, Plourde D, Su J, Gimeno MG, Zhan Y, Galán A, Rzymski T, Mazan M, Masiejczyk M, Faber J, Khoury E, Benoit A, Gagnon N, Dankort D, Journe F, Ghanem GE, Krawczyk CM, Saragovi HU, Piccirillo CA, Sonenberg N, Topisirovic I, Rudd CE, Miller WH Jr, Del Rincón SV. Huang F, et al. Among authors: gagnon n. J Clin Invest. 2021 Apr 15;131(8):e140752. doi: 10.1172/JCI140752. J Clin Invest. 2021. PMID: 33690225 Free PMC article.
Inhibition of the MNK1/2-eIF4E Axis Augments Palbociclib-Mediated Antitumor Activity in Melanoma and Breast Cancer.
Prabhu SA, Moussa O, Gonçalves C, LaPierre JH, Chou H, Huang F, Richard VR, Ferruzo PYM, Guettler EM, Soria-Bretones I, Kirby L, Gagnon N, Su J, Silvester J, Krisna SS, Rose AAN, Sheppard KE, Cescon DW, Mallette FA, Zahedi RP, Borchers CH, Del Rincon SV, Miller WH. Prabhu SA, et al. Among authors: gagnon n. Mol Cancer Ther. 2023 Feb 1;22(2):192-204. doi: 10.1158/1535-7163.MCT-22-0092. Mol Cancer Ther. 2023. PMID: 36722142
Tunable PhenoCycler imaging of the murine pre-clinical tumour microenvironments.
Abraham MJ, Goncalves C, McCallum P, Gupta V, Preston SEJ, Huang F, Chou H, Gagnon N, Johnson NA, Miller WH, Mann KK, Del Rincon SV. Abraham MJ, et al. Among authors: gagnon n. Cell Biosci. 2024 Feb 4;14(1):19. doi: 10.1186/s13578-024-01199-4. Cell Biosci. 2024. PMID: 38311785 Free PMC article.
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.
Huang F, Gonçalves C, Bartish M, Rémy-Sarrazin J, Issa ME, Cordeiro B, Guo Q, Emond A, Attias M, Yang W, Plourde D, Su J, Gimeno MG, Zhan Y, Galán A, Rzymski T, Mazan M, Masiejczyk M, Faber J, Khoury E, Benoit A, Gagnon N, Dankort D, Journe F, Ghanem GE, Krawczyk CM, Saragovi HU, Piccirillo CA, Sonenberg N, Topisirovic I, Rudd CE, Miller WH Jr, Del Rincón SV. Huang F, et al. Among authors: gagnon n. J Clin Invest. 2024 May 1;134(9):e181575. doi: 10.1172/JCI181575. J Clin Invest. 2024. PMID: 38690739 Free PMC article. No abstract available.
Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.
Preston SEJ, Dahabieh MS, Flores González RE, Gonçalves C, Richard VR, Leibovitch M, Dakin E, Papadopoulos T, Lopez Naranjo C, McCallum PA, Huang F, Gagnon N, Perrino S, Zahedi RP, Borchers CH, Jones RG, Brodt P, Miller WH Jr, Del Rincón SV. Preston SEJ, et al. Among authors: gagnon n. Sci Adv. 2024 Sep 13;10(37):eadi7673. doi: 10.1126/sciadv.adi7673. Epub 2024 Sep 13. Sci Adv. 2024. PMID: 39270021 Free PMC article.
Combined Inhibition of MNK Signaling and BET Proteins Reveals TGM2 as a Novel Vulnerability in Melanoma.
Méant A, Moussa O, Lebeau B, Gonçalves C, Richard VR, Cai F, Prabhu SA, Langke M, Guettler EM, Su J, Gagnon N, Zahedi RP, Borchers CH, Miller WH Jr, Del Rincón SV, Witcher M. Méant A, et al. Among authors: gagnon n. J Invest Dermatol. 2024 Oct 1:S0022-202X(24)02160-2. doi: 10.1016/j.jid.2024.07.037. Online ahead of print. J Invest Dermatol. 2024. PMID: 39357785 Free article. No abstract available.
In vitro and in vivo approaches to assess atherosclerosis following exposure to low-dose mixtures of arsenic and cadmium.
Subramaniam NK, Gagnon N, Makhani K, Kukolj N, Mouradian MH, Giles BH, Srikannan H, Fruh V, Meliker J, Wellenius GA, Mann KK. Subramaniam NK, et al. Among authors: gagnon n. Toxicol Appl Pharmacol. 2023 Dec 15;481:116763. doi: 10.1016/j.taap.2023.116763. Epub 2023 Nov 18. Toxicol Appl Pharmacol. 2023. PMID: 37980961 Free PMC article.
140 results