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Page 1
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.
Wang X, Gotchev D, Fan KY, Vega MM, Mani N, McGovern-Gooch K, Cuconati A, Tercero B, Wang X, Carpino P, Maskos K, Centrella PA, Schmitt A, Preuss F, Prasad A, Chen CY, Clark MA, Guilinger JP, Johnstone S, von König K, Keefe AD, Liu J, Turcotte S, Zhang Y, Konz Makino DL, Lam AM, Cole AG, Sofia MJ. Wang X, et al. Among authors: preuss f. J Med Chem. 2024 Nov 14;67(21):19623-19667. doi: 10.1021/acs.jmedchem.4c02009. Epub 2024 Oct 25. J Med Chem. 2024. PMID: 39453309
Lower incidence of grade II-IV acute Graft-versus-Host-Disease in pediatric patients recovering with high Vδ2+ T cells after allogeneic stem cell transplantation with unmanipulated bone marrow grafts: a prospective single-center cohort study.
Müller T, Alasfar L, Preuß F, Zimmermann L, Streitz M, Hundsdörfer P, Eggert A, Schulte J, von Stackelberg A, Oevermann L. Müller T, et al. Among authors: preuss f. Front Immunol. 2024 Jul 29;15:1433785. doi: 10.3389/fimmu.2024.1433785. eCollection 2024. Front Immunol. 2024. PMID: 39136029 Free PMC article.
A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2.
Dederer V, Sanz Murillo M, Karasmanis EP, Hatch KS, Chatterjee D, Preuss F, Abdul Azeez KR, Nguyen LV, Galicia C, Dreier B, Plückthun A, Versees W, Mathea S, Leschziner AE, Reck-Peterson SL, Knapp S. Dederer V, et al. Among authors: preuss f. J Biol Chem. 2024 Jul;300(7):107469. doi: 10.1016/j.jbc.2024.107469. Epub 2024 Jun 12. J Biol Chem. 2024. PMID: 38876305 Free PMC article.
Evidence that the loss of colonic anti-microbial peptides may promote dysbiotic Gram-negative inflammaging-associated bacteria in aging mice.
Forsyth CB, Shaikh M, Engen PA, Preuss F, Naqib A, Palmen BA, Green SJ, Zhang L, Bogin ZR, Lawrence K, Sharma D, Swanson GR, Bishehsari F, Voigt RM, Keshavarzian A. Forsyth CB, et al. Among authors: preuss f. Front Aging. 2024 Mar 4;5:1352299. doi: 10.3389/fragi.2024.1352299. eCollection 2024. Front Aging. 2024. PMID: 38501032 Free PMC article.
Reorganization of pancreas circadian transcriptome with aging.
Sharma D, Wessel CR, Mahdavinia M, Preuss F, Bishehsari F. Sharma D, et al. Among authors: preuss f. Aging (Albany NY). 2023 Aug 29;15(16):7909-7921. doi: 10.18632/aging.204929. Epub 2023 Aug 29. Aging (Albany NY). 2023. PMID: 37647013 Free PMC article.
A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins.
Schwalm MP, Berger LM, Meuter MN, Vasta JD, Corona CR, Röhm S, Berger BT, Farges F, Beinert SM, Preuss F, Morasch V, Rogov VV, Mathea S, Saxena K, Robers MB, Müller S, Knapp S. Schwalm MP, et al. Among authors: preuss f. Front Cell Dev Biol. 2022 May 26;10:886537. doi: 10.3389/fcell.2022.886537. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35721509 Free PMC article.
134 results