Alzubi J - Search Results

1

Cell-Based Models of 'Cytokine Release Syndrome' Endorse CD40L and Granulocyte-Macrophage Colony-Stimulating Factor Knockout in Chimeric Antigen Receptor T Cells as Mitigation Strategy.

Dibas A, Rhiel M, Patel VB, Andrieux G, Boerries M, Cornu TI, Alzubi J, Cathomen T. Dibas A, et al. Among authors: alzubi j. Cells. 2023 Nov 6;12(21):2581. doi: 10.3390/cells12212581. Cells. 2023. PMID: 37947658 Free PMC article.

2

Automated generation of gene-edited CAR T cells at clinical scale.

Alzubi J, Lock D, Rhiel M, Schmitz S, Wild S, Mussolino C, Hildenbeutel M, Brandes C, Rositzka J, Lennartz S, Haas SA, Chmielewski KO, Schaser T, Kaiser A, Cathomen T, Cornu TI. Alzubi J, et al. Mol Ther Methods Clin Dev. 2020 Dec 25;20:379-388. doi: 10.1016/j.omtm.2020.12.008. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2020. PMID: 33575430 Free PMC article.

3

The potential of CAR T cell therapy for prostate cancer.

Wolf P, Alzubi J, Gratzke C, Cathomen T. Wolf P, et al. Among authors: alzubi j. Nat Rev Urol. 2021 Sep;18(9):556-571. doi: 10.1038/s41585-021-00488-8. Epub 2021 Jul 8. Nat Rev Urol. 2021. PMID: 34239139 Review.

4

Genome and Epigenome Editing to Treat Disorders of the Hematopoietic System.

Mussolino C, Alzubi J, Pennucci V, Turchiano G, Cathomen T. Mussolino C, et al. Among authors: alzubi j. Hum Gene Ther. 2017 Nov;28(11):1105-1115. doi: 10.1089/hum.2017.149. Epub 2017 Aug 14. Hum Gene Ther. 2017. PMID: 28806883 Review.

5

Biodegradable Nanocarriers Resembling Extracellular Vesicles Deliver Genetic Material with the Highest Efficiency to Various Cell Types.

Tarakanchikova Y, Alzubi J, Pennucci V, Follo M, Kochergin B, Muslimov A, Skovorodkin I, Vainio S, Antipina MN, Atkin V, Popov A, Meglinski I, Cathomen T, Cornu TI, Gorin DA, Sukhorukov GB, Nazarenko I. Tarakanchikova Y, et al. Among authors: alzubi j. Small. 2020 Jan;16(3):e1904880. doi: 10.1002/smll.201904880. Epub 2019 Dec 16. Small. 2020. PMID: 31840408

6

Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells.

Mosti L, Langner LM, Chmielewski KO, Arbuthnot P, Alzubi J, Cathomen T. Mosti L, et al. Among authors: alzubi j. Gene Ther. 2021 Sep;28(9):602-612. doi: 10.1038/s41434-021-00220-6. Epub 2021 Feb 1. Gene Ther. 2021. PMID: 33526841 Free PMC article.

7

Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model.

Alzubi J, Pallant C, Mussolino C, Howe SJ, Thrasher AJ, Cathomen T. Alzubi J, et al. Sci Rep. 2017 Sep 29;7(1):12475. doi: 10.1038/s41598-017-12750-4. Sci Rep. 2017. PMID: 28963568 Free PMC article.

8

PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model.

Alzubi J, Dettmer-Monaco V, Kuehle J, Thorausch N, Seidl M, Taromi S, Schamel W, Zeiser R, Abken H, Cathomen T, Wolf P. Alzubi J, et al. Mol Ther Oncolytics. 2020 Jun 24;18:226-235. doi: 10.1016/j.omto.2020.06.014. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32728611 Free PMC article.

9

CRISPR-Cas9 based gene editing of the immune checkpoint NKG2A enhances NK cell mediated cytotoxicity against multiple myeloma.

Bexte T, Alzubi J, Reindl LM, Wendel P, Schubert R, Salzmann-Manrique E, von Metzler I, Cathomen T, Ullrich E. Bexte T, et al. Among authors: alzubi j. Oncoimmunology. 2022 May 31;11(1):2081415. doi: 10.1080/2162402X.2022.2081415. eCollection 2022. Oncoimmunology. 2022. PMID: 35694192 Free PMC article.

10

Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery.

Bobis-Wozowicz S, Galla M, Alzubi J, Kuehle J, Baum C, Schambach A, Cathomen T. Bobis-Wozowicz S, et al. Among authors: alzubi j. Sci Rep. 2014 Apr 11;4:4656. doi: 10.1038/srep04656. Sci Rep. 2014. PMID: 24722320 Free PMC article.

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