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115 results

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A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: newman jc. bioRxiv [Preprint]. 2024 May 13:2023.11.02.565382. doi: 10.1101/2023.11.02.565382. bioRxiv. 2024. PMID: 37961209 Free PMC article. Preprint.
Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells.
Ang QY, Alexander M, Newman JC, Tian Y, Cai J, Upadhyay V, Turnbaugh JA, Verdin E, Hall KD, Leibel RL, Ravussin E, Rosenbaum M, Patterson AD, Turnbaugh PJ. Ang QY, et al. Among authors: newman jc. Cell. 2020 Jun 11;181(6):1263-1275.e16. doi: 10.1016/j.cell.2020.04.027. Epub 2020 May 20. Cell. 2020. PMID: 32437658 Free PMC article.
Rationale and protocol for a safety, tolerability and feasibility randomized, parallel group, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.
Stubbs BJ, Alvarez-Azanedo G, Peralta S, Roa-Diaz S, Gray W, Alexander L, Silverman-Martin W, Garcia T, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: newman jc. medRxiv [Preprint]. 2023 Oct 26:2023.10.25.23297571. doi: 10.1101/2023.10.25.23297571. medRxiv. 2023. Update in: PLoS One. 2024 Sep 18;19(9):e0307951. doi: 10.1371/journal.pone.0307951. PMID: 37961234 Free PMC article. Updated. Preprint.
Rationale and protocol for a safety, tolerability and feasibility randomized, parallel arm, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.
Stubbs BJ, Alvarez Azañedo G, Peralta S, Diaz SR, Gray W, Alexander L, Silverman-Martin W, Garcia TY, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: newman jc. PLoS One. 2024 Sep 18;19(9):e0307951. doi: 10.1371/journal.pone.0307951. eCollection 2024. PLoS One. 2024. PMID: 39292659 Free PMC article.
β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain.
Madhavan SS, Roa Diaz S, Peralta S, Nomura M, King CD, Lin A, Bhaumik D, Shah S, Blade T, Gray W, Chamoli M, Eap B, Panda O, Diaz D, Garcia TY, Stubbs BJ, Lithgow GJ, Schilling B, Verdin E, Chaudhuri AR, Newman JC. Madhavan SS, et al. Among authors: newman jc. bioRxiv [Preprint]. 2023 Jul 3:2023.07.03.547547. doi: 10.1101/2023.07.03.547547. bioRxiv. 2023. PMID: 37461525 Free PMC article. Preprint.
Exploratory functional and quality of life outcomes with daily consumption of the ketone ester bis-octanoyl (R)-1,3-butanediol in healthy older adults: a randomized, parallel arm, double-blind, placebo-controlled study.
Stubbs BJ, Stephens EB, Senadheera C, Diaz SR, Peralta S, Alexander L, Silverman-Martin W, Kurtzig J, Fernando BA, Yurkovich JT, Garcia TY, Yukawa M, Morris J, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: newman jc. medRxiv [Preprint]. 2024 Sep 18:2024.09.17.24313811. doi: 10.1101/2024.09.17.24313811. medRxiv. 2024. PMID: 39371165 Free PMC article. Preprint.
Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults in a randomized, parallel arm, double-blind, placebo-controlled, pilot study.
Stubbs BJ, Stephens EB, Senadheera C, Peralta S, Roa-Diaz S, Alexander L, Silverman-Martin W, Garcia TY, Yukawa M, Morris J, Blonquist TM, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: newman jc. J Nutr Health Aging. 2024 Sep;28(9):100329. doi: 10.1016/j.jnha.2024.100329. Epub 2024 Aug 12. J Nutr Health Aging. 2024. PMID: 39137624 Free article. Clinical Trial.
115 results