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MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.
Chen J, Zheng Q, Hicks JL, Trabzonlu L, Ozbek B, Jones T, Vaghasia AM, Larman TC, Wang R, Markowski MC, Denmeade SR, Pienta KJ, Hruban RH, Antonarakis ES, Gupta A, Dang CV, Yegnasubramanian S, De Marzo AM. Chen J, et al. Among authors: ozbek b. JCI Insight. 2023 Dec 22;8(24):e169868. doi: 10.1172/jci.insight.169868. JCI Insight. 2023. PMID: 37971875 Free PMC article.
A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance.
Arriaga JM, Panja S, Alshalalfa M, Zhao J, Zou M, Giacobbe A, Madubata CJ, Kim JY, Rodriguez A, Coleman I, Virk RK, Hibshoosh H, Ertunc O, Ozbek B, Fountain J, Jeffrey Karnes R, Luo J, Antonarakis ES, Nelson PS, Feng FY, Rubin MA, De Marzo AM, Rabadan R, Sims PA, Mitrofanova A, Abate-Shen C. Arriaga JM, et al. Among authors: ozbek b. Nat Cancer. 2020 Nov;1(11):1082-1096. doi: 10.1038/s43018-020-00125-0. Epub 2020 Oct 19. Nat Cancer. 2020. PMID: 34085047 Free PMC article.
Oncogenic gene fusions in nonneoplastic precursors as evidence that bacterial infection can initiate prostate cancer.
Shrestha E, Coulter JB, Guzman W, Ozbek B, Hess MM, Mummert L, Ernst SE, Maynard JP, Meeker AK, Heaphy CM, Haffner MC, De Marzo AM, Sfanos KS. Shrestha E, et al. Among authors: ozbek b. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2018976118. doi: 10.1073/pnas.2018976118. Proc Natl Acad Sci U S A. 2021. PMID: 34341114 Free PMC article.
Supraphysiologic Testosterone Induces Ferroptosis and Activates Immune Pathways through Nucleophagy in Prostate Cancer.
Kumar R, Mendonca J, Owoyemi O, Boyapati K, Thomas N, Kanacharoen S, Coffey M, Topiwala D, Gomes C, Ozbek B, Jones T, Rosen M, Dong L, Wiens S, Brennen WN, Isaacs JT, De Marzo AM, Markowski MC, Antonarakis ES, Qian DZ, Pienta KJ, Pardoll DM, Carducci MA, Denmeade SR, Kachhap SK. Kumar R, et al. Among authors: ozbek b. Cancer Res. 2021 Dec 1;81(23):5948-5962. doi: 10.1158/0008-5472.CAN-20-3607. Epub 2021 Oct 13. Cancer Res. 2021. PMID: 34645612 Free PMC article.
MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression.
Chen J, Zheng Q, Hicks JL, Trabzonlu L, Ozbek B, Jones T, Vaghasia A, Larman TC, Wang R, Markowski MC, Denmeade SR, Pienta KJ, Hruban RH, Antonarakis ES, Gupta A, Dang CV, Yegnasubramanian S, De Marzo AM. Chen J, et al. Among authors: ozbek b. bioRxiv [Preprint]. 2023 Mar 10:2023.02.20.529259. doi: 10.1101/2023.02.20.529259. bioRxiv. 2023. Update in: JCI Insight. 2023 Dec 22;8(24):e169868. doi: 10.1172/jci.insight.169868. PMID: 36865273 Free PMC article. Updated. Preprint.
Bipolar androgen therapy plus nivolumab for patients with metastatic castration-resistant prostate cancer: the COMBAT phase II trial.
Markowski MC, Taplin ME, Aggarwal R, Sena LA, Wang H, Qi H, Lalji A, Sinibaldi V, Carducci MA, Paller CJ, Marshall CH, Eisenberger MA, Sanin DE, Yegnasubramanian S, Gomes-Alexandre C, Ozbek B, Jones T, De Marzo AM, Denmeade SR, Antonarakis ES. Markowski MC, et al. Among authors: ozbek b. Nat Commun. 2024 Jan 2;15(1):14. doi: 10.1038/s41467-023-44514-2. Nat Commun. 2024. PMID: 38167882 Free PMC article. Clinical Trial.
PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.
Lønborg J, Jabbari R, Sabbah M, Veien KT, Niemelä M, Freeman P, Linder R, Ioanes D, Terkelsen CJ, Kajander OA, Koul S, Savontaus M, Karjalainen P, Erglis A, Minkkinen M, Sørensen R, Tilsted HH, Holmvang L, Bieliauskas G, Ellert J, Piuhola J, Eftekhari A, Angerås O, Rück A, Christiansen EH, Jørgensen T, Özbek BT, Glinge C, Søndergaard L, De Backer O, Engstrøm T; NOTION-3 Study Group. Lønborg J, et al. Among authors: ozbek bt. N Engl J Med. 2024 Aug 31. doi: 10.1056/NEJMoa2401513. Online ahead of print. N Engl J Med. 2024. PMID: 39216095
63 results