Kalke K - Search Results

1

Attenuated Replication-Competent Herpes Simplex Virus Expressing an ECM-Modifying Transgene Hyaluronan Synthase 2 of Naked Mole Rat in Oncolytic Gene Therapy.

Palomäki J, Kalke K, Orpana J, Lund L, Frejborg F, Paavilainen H, Järveläinen H, Hukkanen V. Palomäki J, et al. Among authors: kalke k. Microorganisms. 2023 Oct 29;11(11):2657. doi: 10.3390/microorganisms11112657. Microorganisms. 2023. PMID: 38004669 Free PMC article.

2

Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity.

Kalke K, Lehtinen J, Gnjatovic J, Lund LM, Nyman MC, Paavilainen H, Orpana J, Lasanen T, Frejborg F, Levanova AA, Vuorinen T, Poranen MM, Hukkanen V. Kalke K, et al. Viruses. 2020 Dec 13;12(12):1434. doi: 10.3390/v12121434. Viruses. 2020. PMID: 33322225 Free PMC article.

3

The In Vitro Replication, Spread, and Oncolytic Potential of Finnish Circulating Strains of Herpes Simplex Virus Type 1.

Kalke K, Orpana J, Lasanen T, Esparta O, Lund LM, Frejborg F, Vuorinen T, Paavilainen H, Hukkanen V. Kalke K, et al. Viruses. 2022 Jun 13;14(6):1290. doi: 10.3390/v14061290. Viruses. 2022. PMID: 35746761 Free PMC article.

4

Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells.

Kalke K, Lund LM, Nyman MC, Levanova AA, Urtti A, Poranen MM, Hukkanen V, Paavilainen H. Kalke K, et al. PLoS Pathog. 2022 Jul 6;18(7):e1010688. doi: 10.1371/journal.ppat.1010688. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35793357 Free PMC article.

5

Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity.

Levanova AA, Kalke KM, Lund LM, Sipari N, Sadeghi M, Nyman MC, Paavilainen H, Hukkanen V, Poranen MM. Levanova AA, et al. Antiviral Res. 2020 Oct;182:104916. doi: 10.1016/j.antiviral.2020.104916. Epub 2020 Aug 13. Antiviral Res. 2020. PMID: 32798603 Free PMC article.

6

Native RNA Purification Method for Small RNA Molecules Based on Asymmetrical Flow Field-Flow Fractionation.

Levanova AA, Lampi M, Kalke K, Hukkanen V, Poranen MM, Eskelin K. Levanova AA, et al. Among authors: kalke k. Pharmaceuticals (Basel). 2022 Feb 21;15(2):261. doi: 10.3390/ph15020261. Pharmaceuticals (Basel). 2022. PMID: 35215370 Free PMC article.

7

Single therapeutic dose of an antiviral UL29 siRNA swarm diminishes symptoms and viral load of mice infected intranasally with HSV-1.

Lasanen T, Frejborg F, Lund LM, Nyman MC, Orpana J, Habib H, Alaollitervo S, Levanova AA, Poranen MM, Hukkanen V, Kalke K. Lasanen T, et al. Among authors: kalke k. Smart Med. 2023 May 10;2(2):e20230009. doi: 10.1002/SMMD.20230009. eCollection 2023 May. Smart Med. 2023. PMID: 39188276 Free PMC article.

8

Current landscape in antiviral drug development against herpes simplex virus infections.

Frejborg F, Kalke K, Hukkanen V. Frejborg F, et al. Among authors: kalke k. Smart Med. 2022 Dec 16;1(1):e20220004. doi: 10.1002/SMMD.20220004. eCollection 2022 Dec. Smart Med. 2022. PMID: 39188739 Free PMC article. Review.

9

Integrating clinical genetics in cardiology: Current practices and recommendations for education.

Scherr CL, Kalke K, Ramesh S, Fakhari H, Dellefave-Castillo LM, Smith ME, Kalny C, McNally EM, Rasmussen-Torvik LJ. Scherr CL, et al. Among authors: kalke k. Genet Med. 2022 May;24(5):1054-1061. doi: 10.1016/j.gim.2022.02.003. Epub 2022 Mar 24. Genet Med. 2022. PMID: 35339388 Free PMC article.

10

Practitioners' Confidence and Desires for Education in Cardiovascular and Sudden Cardiac Death Genetics.

Lopez Santibanez Jacome L, Dellefave-Castillo LM, Wicklund CA, Scherr CL, Duquette D, Webster G, Smith ME, Kalke K, Gordon AS, De Berg K, McNally EM, Rasmussen-Torvik LJ. Lopez Santibanez Jacome L, et al. Among authors: kalke k. J Am Heart Assoc. 2022 Apr 5;11(7):e023763. doi: 10.1161/JAHA.121.023763. Epub 2022 Mar 24. J Am Heart Assoc. 2022. PMID: 35322684 Free PMC article.

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