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Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells.
Sobinoff AP, Di Maro S, Low RRJ, Benedetti R, Tomassi S, D'Aniello A, Russo R, Baglivo I, Chianese U, Pedone PV, Chambery A, Cesare AJ, Altucci L, Pickett HA, Cosconati S. Sobinoff AP, et al. Among authors: cesare aj. Cell Chem Biol. 2023 Dec 21;30(12):1652-1665.e6. doi: 10.1016/j.chembiol.2023.11.008. Epub 2023 Dec 7. Cell Chem Biol. 2023. PMID: 38065101
Telomere Loop Dynamics in Chromosome End Protection.
Van Ly D, Low RRJ, Frölich S, Bartolec TK, Kafer GR, Pickett HA, Gaus K, Cesare AJ. Van Ly D, et al. Among authors: cesare aj. Mol Cell. 2018 Aug 16;71(4):510-525.e6. doi: 10.1016/j.molcel.2018.06.025. Epub 2018 Jul 19. Mol Cell. 2018. PMID: 30033372 Free article.
Telomerase promotes formation of a telomere protective complex in cancer cells.
Perera ON, Sobinoff AP, Teber ET, Harman A, Maritz MF, Yang SF, Pickett HA, Cesare AJ, Arthur JW, MacKenzie KL, Bryan TM. Perera ON, et al. Among authors: cesare aj. Sci Adv. 2019 Oct 2;5(10):eaav4409. doi: 10.1126/sciadv.aav4409. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31616780 Free PMC article.
Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes.
Ginn SL, Amaya AK, Liao SHY, Zhu E, Cunningham SC, Lee M, Hallwirth CV, Logan GJ, Tay SS, Cesare AJ, Pickett HA, Grompe M, Dilworth K, Lisowski L, Alexander IE. Ginn SL, et al. Among authors: cesare aj. JHEP Rep. 2019 Dec 27;2(1):100065. doi: 10.1016/j.jhepr.2019.100065. eCollection 2020 Feb. JHEP Rep. 2019. PMID: 32039406 Free PMC article.
47 results