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Page 1
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: moran losada p. Res Sq [Preprint]. 2024 May 30:rs.3.rs-4407236. doi: 10.21203/rs.3.rs-4407236/v1. Res Sq. 2024. PMID: 38853828 Free PMC article. Preprint.
Post-translational modifications linked to preclinical Alzheimer's disease-related pathological and cognitive changes.
Abiose O, Rutledge J, Moran-Losada P, Belloy ME, Wilson EN, He Z, Trelle AN, Channappa D, Romero A, Park J, Yutsis MV, Sha SJ, Andreasson KI, Poston KL, Henderson VW, Wagner AD, Wyss-Coray T, Mormino EC. Abiose O, et al. Among authors: moran losada p. Alzheimers Dement. 2024 Mar;20(3):1851-1867. doi: 10.1002/alz.13576. Epub 2023 Dec 25. Alzheimers Dement. 2024. PMID: 38146099 Free PMC article.
Organ aging signatures in the plasma proteome track health and disease.
Oh HS, Rutledge J, Nachun D, Pálovics R, Abiose O, Moran-Losada P, Channappa D, Urey DY, Kim K, Sung YJ, Wang L, Timsina J, Western D, Liu M, Kohlfeld P, Budde J, Wilson EN, Guen Y, Maurer TM, Haney M, Yang AC, He Z, Greicius MD, Andreasson KI, Sathyan S, Weiss EF, Milman S, Barzilai N, Cruchaga C, Wagner AD, Mormino E, Lehallier B, Henderson VW, Longo FM, Montgomery SB, Wyss-Coray T. Oh HS, et al. Among authors: moran losada p. Nature. 2023 Dec;624(7990):164-172. doi: 10.1038/s41586-023-06802-1. Epub 2023 Dec 6. Nature. 2023. PMID: 38057571 Free PMC article.
Atlas of the aging mouse brain reveals white matter as vulnerable foci.
Hahn O, Foltz AG, Atkins M, Kedir B, Moran-Losada P, Guldner IH, Munson C, Kern F, Pálovics R, Lu N, Zhang H, Kaur A, Hull J, Huguenard JR, Grönke S, Lehallier B, Partridge L, Keller A, Wyss-Coray T. Hahn O, et al. Among authors: moran losada p. Cell. 2023 Sep 14;186(19):4117-4133.e22. doi: 10.1016/j.cell.2023.07.027. Epub 2023 Aug 16. Cell. 2023. PMID: 37591239 Free PMC article.
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: moran losada p. bioRxiv [Preprint]. 2023 Mar 27:2023.03.27.534444. doi: 10.1101/2023.03.27.534444. bioRxiv. 2023. PMID: 37034684 Free PMC article. Preprint.
The Cystic Fibrosis Upper and Lower Airway Metagenome.
Pienkowska K, Pust MM, Gessner M, Gaedcke S, Thavarasa A, Rosenboom I, Morán Losada P, Minso R, Arnold C, Hedtfeld S, Dorda M, Wiehlmann L, Mainz JG, Klockgether J, Tümmler B. Pienkowska K, et al. Among authors: moran losada p. Microbiol Spectr. 2023 Mar 9;11(2):e0363322. doi: 10.1128/spectrum.03633-22. Online ahead of print. Microbiol Spectr. 2023. PMID: 36892308 Free PMC article.
Correction: Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism.
Urresti J, Zhang P, Moran-Losada P, Yu NK, Negraes PD, Trujillo CA, Antaki D, Amar M, Chau K, Pramod AB, Diedrich J, Tejwani L, Romero S, Sebat J, Yates Iii JR, Muotri AR, Iakoucheva LM. Urresti J, et al. Among authors: moran losada p. Mol Psychiatry. 2021 Dec;26(12):7581. doi: 10.1038/s41380-021-01289-6. Mol Psychiatry. 2021. PMID: 34548630 Free PMC article. No abstract available.
Cortical organoids model early brain development disrupted by 16p11.2 copy number variants in autism.
Urresti J, Zhang P, Moran-Losada P, Yu NK, Negraes PD, Trujillo CA, Antaki D, Amar M, Chau K, Pramod AB, Diedrich J, Tejwani L, Romero S, Sebat J, Yates Iii JR, Muotri AR, Iakoucheva LM. Urresti J, et al. Among authors: moran losada p. Mol Psychiatry. 2021 Dec;26(12):7560-7580. doi: 10.1038/s41380-021-01243-6. Epub 2021 Aug 26. Mol Psychiatry. 2021. PMID: 34433918 Free PMC article.
Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling.
Amar M, Pramod AB, Yu NK, Herrera VM, Qiu LR, Moran-Losada P, Zhang P, Trujillo CA, Ellegood J, Urresti J, Chau K, Diedrich J, Chen J, Gutierrez J, Sebat J, Ramanathan D, Lerch JP, Yates JR 3rd, Muotri AR, Iakoucheva LM. Amar M, et al. Among authors: moran losada p. Mol Psychiatry. 2021 Jul;26(7):3586-3613. doi: 10.1038/s41380-021-01052-x. Epub 2021 Mar 16. Mol Psychiatry. 2021. PMID: 33727673 Free PMC article.
Undulating changes in human plasma proteome profiles across the lifespan.
Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C, Milman S, Barzilai N, Wyss-Coray T. Lehallier B, et al. Among authors: moran losada p. Nat Med. 2019 Dec;25(12):1843-1850. doi: 10.1038/s41591-019-0673-2. Epub 2019 Dec 5. Nat Med. 2019. PMID: 31806903 Free PMC article.
17 results