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Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1-42.
Kober DL, Stuchell-Brereton MD, Kluender CE, Dean HB, Strickland MR, Steinberg DF, Nelson SS, Baban B, Holtzman DM, Frieden C, Alexander-Brett J, Roberson ED, Song Y, Brett TJ. Kober DL, et al. Among authors: strickland mr. Alzheimers Dement. 2020 Oct 8:10.1002/alz.12194. doi: 10.1002/alz.12194. Online ahead of print. Alzheimers Dement. 2020. PMID: 33090700 Free PMC article.
Activated microglia mitigate Aβ-associated tau seeding and spreading.
Gratuze M, Chen Y, Parhizkar S, Jain N, Strickland MR, Serrano JR, Colonna M, Ulrich JD, Holtzman DM. Gratuze M, et al. Among authors: strickland mr. J Exp Med. 2021 Aug 2;218(8):e20210542. doi: 10.1084/jem.20210542. Epub 2021 Jun 8. J Exp Med. 2021. PMID: 34100905 Free PMC article.
Cell autonomous role of border associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury.
Iadecola C, Anfray A, Schaeffer S, Hattori Y, Santisteban M, Casey N, Wang G, Strickland M, Zhou P, Holtzman D, Anrather J, Park L. Iadecola C, et al. Res Sq [Preprint]. 2023 Aug 4:rs.3.rs-3222611. doi: 10.21203/rs.3.rs-3222611/v1. Res Sq. 2023. Update in: Nat Neurosci. 2024 Nov;27(11):2138-2151. doi: 10.1038/s41593-024-01757-6. PMID: 37577565 Free PMC article. Updated. Preprint.
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.
Chen Y, Song S, Parhizkar S, Lord J, Zhu Y, Strickland MR, Wang C, Park J, Tabor GT, Jiang H, Li K, Davis AA, Yuede CM, Colonna M, Ulrich JD, Holtzman DM. Chen Y, et al. Among authors: strickland mr. Cell. 2024 Jan 18;187(2):428-445.e20. doi: 10.1016/j.cell.2023.11.029. Epub 2023 Dec 11. Cell. 2024. PMID: 38086389
41 results