Sjöstedt N - Search Results

1

Alterations in zonal distribution and plasma membrane localization of hepatocyte bile acid transporters in patients with NAFLD.

Murphy WA, Diehl AM, Loop MS, Fu D, Guy CD, Abdelmalek MF, Karachaliou GS, Sjöstedt N, Neuhoff S, Honkakoski P, Brouwer KLR. Murphy WA, et al. Among authors: sjostedt n. Hepatol Commun. 2024 Feb 14;8(3):e0377. doi: 10.1097/HC9.0000000000000377. eCollection 2024 Mar 1. Hepatol Commun. 2024. PMID: 38381537 Free PMC article.

2

Membrane transporters in drug development and as determinants of precision medicine.

Galetin A, Brouwer KLR, Tweedie D, Yoshida K, Sjöstedt N, Aleksunes L, Chu X, Evers R, Hafey MJ, Lai Y, Matsson P, Riselli A, Shen H, Sparreboom A, Varma MVS, Yang J, Yang X, Yee SW, Zamek-Gliszczynski MJ, Zhang L, Giacomini KM. Galetin A, et al. Among authors: sjostedt n. Nat Rev Drug Discov. 2024 Apr;23(4):255-280. doi: 10.1038/s41573-023-00877-1. Epub 2024 Jan 24. Nat Rev Drug Discov. 2024. PMID: 38267543 Free PMC article. Review.

3

In vitro identification of decreased function phenotype ABCG2 variants.

Suominen L, Sjöstedt N, Vellonen KS, Gynther M, Auriola S, Kidron H. Suominen L, et al. Among authors: sjostedt n. Eur J Pharm Sci. 2023 Sep 1;188:106527. doi: 10.1016/j.ejps.2023.106527. Epub 2023 Jul 13. Eur J Pharm Sci. 2023. PMID: 37451410 Free article.

4

Novel inhibitors of breast cancer resistance protein (BCRP, ABCG2) among marketed drugs.

Deng F, Sjöstedt N, Santo M, Neuvonen M, Niemi M, Kidron H. Deng F, et al. Among authors: sjostedt n. Eur J Pharm Sci. 2023 Feb 1;181:106362. doi: 10.1016/j.ejps.2022.106362. Epub 2022 Dec 15. Eur J Pharm Sci. 2023. PMID: 36529162 Free article.

5

Effect of Carbidopa Dose on Levodopa Pharmacokinetics With and Without Catechol-O-Methyltransferase Inhibition in Healthy Subjects.

Tuunainen J, Sjöstedt N, Vahteristo M, Ellmén J, Kuoppamäki M, Rouru J, Yliperttula M. Tuunainen J, et al. Among authors: sjostedt n. Eur J Drug Metab Pharmacokinet. 2023 Jan;48(1):23-34. doi: 10.1007/s13318-022-00800-w. Epub 2022 Oct 30. Eur J Drug Metab Pharmacokinet. 2023. PMID: 36309950 Clinical Trial.

6

Functional in vitro characterization of SLCO1B1 variants and simulation of the clinical pharmacokinetic impact of impaired OATP1B1 function.

Kiander W, Sjöstedt N, Manninen R, Jaakkonen L, Vellonen KS, Neuvonen M, Niemi M, Auriola S, Kidron H. Kiander W, et al. Among authors: sjostedt n. Eur J Pharm Sci. 2022 Sep 1;176:106246. doi: 10.1016/j.ejps.2022.106246. Epub 2022 Jun 22. Eur J Pharm Sci. 2022. PMID: 35752377 Free article.

7

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH).

Murphy WA, Adiwidjaja J, Sjöstedt N, Yang K, Beaudoin JJ, Spires J, Siler SQ, Neuhoff S, Brouwer KLR. Murphy WA, et al. Among authors: sjostedt n. Clin Pharmacol Ther. 2023 Feb;113(2):275-297. doi: 10.1002/cpt.2614. Epub 2022 Jun 2. Clin Pharmacol Ther. 2023. PMID: 35429164 Free PMC article. Review.

8

Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium.

Brouwer KLR, Evers R, Hayden E, Hu S, Li CY, Meyer Zu Schwabedissen HE, Neuhoff S, Oswald S, Piquette-Miller M, Saran C, Sjöstedt N, Sprowl JA, Stahl SH, Yue W. Brouwer KLR, et al. Among authors: sjostedt n. Clin Pharmacol Ther. 2022 Sep;112(3):461-484. doi: 10.1002/cpt.2605. Epub 2022 May 24. Clin Pharmacol Ther. 2022. PMID: 35390174 Free PMC article. Review.

9

The Role of Uptake and Efflux Transporters in the Disposition of Glucuronide and Sulfate Conjugates.

Järvinen E, Deng F, Kiander W, Sinokki A, Kidron H, Sjöstedt N. Järvinen E, et al. Among authors: sjostedt n. Front Pharmacol. 2022 Jan 13;12:802539. doi: 10.3389/fphar.2021.802539. eCollection 2021. Front Pharmacol. 2022. PMID: 35095509 Free PMC article. Review.

10

Identification of Key Amino Acids that Impact Organic Solute Transporter α/β (OSTα/β).

Murphy WA, Beaudoin JJ, Laitinen T, Sjöstedt N, Malinen MM, Ho H, Swaan PW, Honkakoski P, Brouwer KLR. Murphy WA, et al. Among authors: sjostedt n. Mol Pharmacol. 2021 Dec;100(6):599-608. doi: 10.1124/molpharm.121.000345. Epub 2021 Oct 1. Mol Pharmacol. 2021. PMID: 34599072 Free PMC article.

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