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Tackling the translational challenges of multi-omics research in the realm of European personalised medicine: A workshop report.
Oldoni E, Saunders G, Bietrix F, Garcia Bermejo ML, Niehues A, 't Hoen PAC, Nordlund J, Hajduch M, Scherer A, Kivinen K, Pitkänen E, Mäkela TP, Gut I, Scollen S, Kozera Ł, Esteller M, Shi L, Ussi A, Andreu AL, van Gool AJ. Oldoni E, et al. Front Mol Biosci. 2022 Oct 13;9:974799. doi: 10.3389/fmolb.2022.974799. eCollection 2022. Front Mol Biosci. 2022. PMID: 36310597 Free PMC article.
Computational approaches for network-based integrative multi-omics analysis.
Agamah FE, Bayjanov JR, Niehues A, Njoku KF, Skelton M, Mazandu GK, Ederveen THA, Mulder N, Chimusa ER, 't Hoen PAC. Agamah FE, et al. Front Mol Biosci. 2022 Nov 14;9:967205. doi: 10.3389/fmolb.2022.967205. eCollection 2022. Front Mol Biosci. 2022. PMID: 36452456 Free PMC article. Review.
Ndufs4 knockout mice with isolated complex I deficiency engage a futile adaptive brain response.
van de Wal MAE, Doornbos C, Bibbe JM, Homberg JR, van Karnebeek C, Huynen MA, Keijer J, van Schothorst EM, 't Hoen PAC, Janssen MCH, Adjobo-Hermans MJW, Wieckowski MR, Koopman WJH. van de Wal MAE, et al. Among authors: t hoen pac. Biochim Biophys Acta Proteins Proteom. 2024 Oct 11;1873(1):141055. doi: 10.1016/j.bbapap.2024.141055. Online ahead of print. Biochim Biophys Acta Proteins Proteom. 2024. PMID: 39395749 Free article.
Integrative analysis of multi-omics data reveals importance of collagen and the PI3K AKT signalling pathway in CAKUT.
Bayjanov JR, Doornbos C, Ozisik O, Shin W, Queralt-Rosinach N, Wijnbergen D, Saulnier-Blache JS, Schanstra JP, Buffin-Meyer B, Klein J, Fernández JM, Kaliyaperumal R, Baudot A, 't Hoen PAC, Ehrhart F. Bayjanov JR, et al. Among authors: t hoen pac. Sci Rep. 2024 Sep 5;14(1):20731. doi: 10.1038/s41598-024-71721-8. Sci Rep. 2024. PMID: 39237660 Free PMC article.
Comprehensive reanalysis for CNVs in ES data from unsolved rare disease cases results in new diagnoses.
Demidov G, Yaldiz B, Garcia-Pelaez J, de Boer E, Schuermans N, Van de Vondel L, Paramonov I, Johansson LF, Musacchia F, Benetti E, Bullich G, Sablauskas K, Beltran S, Gilissen C, Hoischen A, Ossowski S, de Voer R, Lohmann K, Oliveira C, Topf A, Vissers LELM; Solve-RD Consortium; Laurie S. Demidov G, et al. NPJ Genom Med. 2024 Oct 26;9(1):49. doi: 10.1038/s41525-024-00436-6. NPJ Genom Med. 2024. PMID: 39461972 Free PMC article.
233 results