Wang X - Search Results

1

Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice.

Yang C, Meng Y, Wang X, Li X, Yu T, Liao W, Xie W, Jiang Q, Wang H, Shi C, Jiao W, Bian X, Hu F, Wang X, Liu Y, Zhang L, Wang K, Sun Q. Yang C, et al. Among authors: wang x, wang h, wang k. J Med Chem. 2024 Apr 25;67(8):6344-6364. doi: 10.1021/acs.jmedchem.3c02323. Epub 2024 Feb 23. J Med Chem. 2024. PMID: 38393821

2

Novel 8-deaza-5,6,7,8-tetrahydroaminopterin derivatives as dihydrofolate inhibitor: design, synthesis and antifolate activity.

Zhang Z, Wu J, Ran F, Guo Y, Tian R, Zhou S, Wang X, Liu Z, Zhang L, Cui J, Liu J. Zhang Z, et al. Among authors: wang x. Eur J Med Chem. 2009 Feb;44(2):764-71. doi: 10.1016/j.ejmech.2008.04.017. Epub 2008 May 4. Eur J Med Chem. 2009. PMID: 18555562

3

Synthesis and biological evaluation of novel 2-arylalkylthio-4-amino-6-benzyl pyrimidines as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

Qin H, Liu C, Zhang J, Guo Y, Zhang S, Zhang Z, Wang X, Zhang L, Liu J. Qin H, et al. Among authors: wang x. Bioorg Med Chem Lett. 2010 May 1;20(9):3003-5. doi: 10.1016/j.bmcl.2009.04.051. Epub 2009 Apr 18. Bioorg Med Chem Lett. 2010. PMID: 20347295

4

Design, synthesis, and biological evaluation of 1-[(2-benzyloxyl/alkoxyl)methyl]-5-halo-6-aryluracils as potent HIV-1 non-nucleoside reverse transcriptase inhibitors with an improved drug resistance profile.

Wang X, Zhang J, Huang Y, Wang R, Zhang L, Qiao K, Li L, Liu C, Ouyang Y, Xu W, Zhang Z, Zhang L, Shao Y, Jiang S, Ma L, Liu J. Wang X, et al. Among authors: wang r. J Med Chem. 2012 Mar 8;55(5):2242-50. doi: 10.1021/jm201506e. Epub 2012 Feb 17. J Med Chem. 2012. PMID: 22283377 Free PMC article.

5

Study on 2-arylthio-5-iodo pyrimidine derivatives as novel nonnucleoside inhibitors against hepatitis B virus DNA replication.

Zhao J, Tu J, Fan N, Chen X, Lu F, Zhang Y, Zhang L, Tian C, Zhang Z, Liu J, Wang X. Zhao J, et al. Among authors: wang x. Future Med Chem. 2016 May;8(7):751-63. doi: 10.4155/fmc.16.13. Epub 2016 May 13. Future Med Chem. 2016. PMID: 27172826

6

Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2-d]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase.

Wang M, Yang J, Yuan M, Xue L, Li H, Tian C, Wang X, Liu J, Zhang Z. Wang M, et al. Among authors: wang x. Eur J Med Chem. 2017 Mar 10;128:88-97. doi: 10.1016/j.ejmech.2017.01.033. Epub 2017 Jan 25. Eur J Med Chem. 2017. PMID: 28152430

7

Synthesis and biological evaluation of 2,6-disubstituted-9H-purine, 2,4-disubstitued-thieno[3,2-d]pyrimidine and -7H-pyrrolo[2,3-d]pyrimidine analogues as novel CHK1 inhibitors.

Tian C, Han Z, Li Y, Wang M, Yang J, Wang X, Zhang Z, Liu J. Tian C, et al. Among authors: wang x, wang m. Eur J Med Chem. 2018 May 10;151:836-848. doi: 10.1016/j.ejmech.2018.03.075. Epub 2018 Mar 28. Eur J Med Chem. 2018. PMID: 29684894

8

Structure-activity relationship studies of (E)-3,4-dihydroxystyryl alkyl sulfones as novel neuroprotective agents based on improved antioxidant, anti-inflammatory activities and BBB permeability.

Chen Y, Wu B, Hao Y, Liu Y, Zhang Z, Tian C, Ning X, Guo Y, Liu J, Wang X. Chen Y, et al. Among authors: wang x. Eur J Med Chem. 2019 Jun 1;171:420-433. doi: 10.1016/j.ejmech.2019.03.044. Epub 2019 Mar 21. Eur J Med Chem. 2019. PMID: 30928712

9

Corrigendum to <'Synthesis and biological evaluation of 2,6-disubstituted-9H-purine, 2,4-disubstitued-thieno[3,2-d]pyrimidine and -7H-pyrrolo[2,3-d] pyrimidine analogues as novel CHK1 inhibitors' [Eur. J. Med. Chem. 151 (2018) 836-848].

Tian C, Han Z, Li Y, Wang M, Yang J, Wang X, Zhang Z, Liu J. Tian C, et al. Among authors: wang x, wang m. Eur J Med Chem. 2019 Jul 1;173:184. doi: 10.1016/j.ejmech.2019.04.011. Epub 2019 Apr 16. Eur J Med Chem. 2019. PMID: 31003059 No abstract available.

10

Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors.

Wang X, Xiao H, Wang J, Huang Z, Peng G, Xie W, Bian X, Liu H, Shi C, Yang T, Li X, Gao J, Meng Y, Jiang Q, Chen W, Hu F, Wei N, Wang X, Zhang L, Wang K, Sun Q. Wang X, et al. Among authors: wang k, wang j. J Med Chem. 2021 Aug 26;64(16):12379-12396. doi: 10.1021/acs.jmedchem.1c01058. Epub 2021 Aug 10. J Med Chem. 2021. PMID: 34374537

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