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Page 1
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment.
He XY, Gao Y, Ng D, Michalopoulou E, George S, Adrover JM, Sun L, Albrengues J, Daßler-Plenker J, Han X, Wan L, Wu XS, Shui LS, Huang YH, Liu B, Su C, Spector DL, Vakoc CR, Van Aelst L, Egeblad M. He XY, et al. Among authors: vakoc cr. Cancer Cell. 2024 Mar 11;42(3):474-486.e12. doi: 10.1016/j.ccell.2024.01.013. Epub 2024 Feb 22. Cancer Cell. 2024. PMID: 38402610
Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies.
He T, Xiao L, Qiao Y, Klingbeil O, Young E, Wu XS, Mannan R, Mahapatra S, Eyunni S, Ching-Yi Tien J, Wang X, Zheng Y, Kim N, Zheng H, Hou S, Su F, Miner SJ, Mehra R, Cao X, Abbineni C, Samajdar S, Ramachandra M, Parolia A, Vakoc CR, Chinnaiyan AM. He T, et al. Among authors: vakoc cr. bioRxiv [Preprint]. 2024 May 24:2024.01.22.576669. doi: 10.1101/2024.01.22.576669. bioRxiv. 2024. Update in: Cancer Cell. 2024 Aug 12;42(8):1336-1351.e9. doi: 10.1016/j.ccell.2024.06.006. PMID: 38328238 Free PMC article. Updated. Preprint.
Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function.
Swamynathan MM, Kuang S, Watrud KE, Doherty MR, Gineste C, Mathew G, Gong GQ, Cox H, Cheng E, Reiss D, Kendall J, Ghosh D, Reczek CR, Zhao X, Herzka T, Špokaitė S, Dessus AN, Kim ST, Klingbeil O, Liu J, Nowak DG, Alsudani H, Wee TL, Park Y, Minicozzi F, Rivera K, Almeida AS, Chang K, Chakrabarty RP, Wilkinson JE, Gimotty PA, Diermeier SD, Egeblad M, Vakoc CR, Locasale JW, Chandel NS, Janowitz T, Hicks JB, Wigler M, Pappin DJ, Williams RL, Cifani P, Tuveson DA, Laporte J, Trotman LC. Swamynathan MM, et al. Among authors: vakoc cr. Science. 2024 Oct 25;386(6720):eadk9167. doi: 10.1126/science.adk9167. Epub 2024 Oct 25. Science. 2024. PMID: 39446948
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks.
Cassandri M, Porrazzo A, Pomella S, Noce B, Zwergel C, Aiello FA, Vulcano F, Milazzo L, Camero S, Pajalunga D, Spada M, Manzi V, Gravina GL, Codenotti S, Piccione M, Tomaciello M, Signore M, Barillari G, Marchese C, Fanzani A, De Angelis B, Quintarelli C, Vakoc CR, Chen EY, Megiorni F, Locatelli F, Valente S, Mai A, Rota R, Marampon F. Cassandri M, et al. Among authors: vakoc cr. Cell Death Discov. 2024 Aug 6;10(1):351. doi: 10.1038/s41420-024-02115-y. Cell Death Discov. 2024. PMID: 39107280 Free PMC article.
MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer.
Klingbeil O, Skopelitis D, Tonelli C, Yoshimoto T, Alpsoy A, Panepinto MC, Minicozzi F, Merrill JR, Cafiero AM, Aggarwal D, Russo S, Ha T, Demerdash OE, Wee TL, Spector DL, Lyons SK, Tuveson DA, Cifani P, Vakoc CR. Klingbeil O, et al. Among authors: vakoc cr. Cancer Discov. 2024 Jul 26. doi: 10.1158/2159-8290.CD-23-1529. Online ahead of print. Cancer Discov. 2024. PMID: 39058094
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer.
Duplaquet L, So K, Ying AW, Pal Choudhuri S, Li X, Xu GD, Li Y, Qiu X, Li R, Singh S, Wu XS, Hamilton S, Chien VD, Liu Q, Qi J, Somerville TDD, Heiling HM, Mazzola E, Lee Y, Zoller T, Vakoc CR, Doench JG, Forrester WC, Abrams T, Long HW, Niederst MJ, Drapkin BJ, Kadoch C, Oser MG. Duplaquet L, et al. Among authors: vakoc cr. Cancer Cell. 2024 Aug 12;42(8):1352-1369.e13. doi: 10.1016/j.ccell.2024.06.012. Epub 2024 Jul 18. Cancer Cell. 2024. PMID: 39029464 Free article.
Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies.
He T, Xiao L, Qiao Y, Klingbeil O, Young E, Wu XS, Mannan R, Mahapatra S, Redin E, Cho H, Bao Y, Kandarpa M, Ching-Yi Tien J, Wang X, Eyunni S, Zheng Y, Kim N, Zheng H, Hou S, Su F, Miner SJ, Mehra R, Cao X, Abbineni C, Samajdar S, Ramachandra M, Dhanasekaran SM, Talpaz M, Parolia A, Rudin CM, Vakoc CR, Chinnaiyan AM. He T, et al. Among authors: vakoc cr. Cancer Cell. 2024 Aug 12;42(8):1336-1351.e9. doi: 10.1016/j.ccell.2024.06.006. Epub 2024 Jul 18. Cancer Cell. 2024. PMID: 39029462 Free article.
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.
Maia-Silva D, Cunniff PJ, Schier AC, Skopelitis D, Trousdell MC, Moresco P, Gao Y, Kechejian V, He XY, Sahin Y, Wan L, Alpsoy A, Liverpool J, Krainer AR, Egeblad M, Spector DL, Fearon DT, Dos Santos CO, Taatjes DJ, Vakoc CR. Maia-Silva D, et al. Among authors: vakoc cr. Nat Genet. 2024 Jul;56(7):1377-1385. doi: 10.1038/s41588-024-01790-y. Epub 2024 Jun 17. Nat Genet. 2024. PMID: 38886586
CHD2 Regulates Neuron-Glioma Interactions in Pediatric Glioma.
Zhang X, Duan S, Apostolou PE, Wu X, Watanabe J, Gallitto M, Barron T, Taylor KR, Woo PJ, Hua X, Zhou H, Wei HJ, McQuillan N, Kang KD, Friedman GK, Canoll PD, Chang K, Wu CC, Hashizume R, Vakoc CR, Monje M, McKhann GM 2nd, Gogos JA, Zhang Z. Zhang X, et al. Among authors: vakoc cr. Cancer Discov. 2024 Sep 4;14(9):1732-1754. doi: 10.1158/2159-8290.CD-23-0012. Cancer Discov. 2024. PMID: 38767413
136 results