Henderson MX - Search Results

1

LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression.

Lubben N, Brynildsen JK, Webb CM, Li HL, Leyns CEG, Changolkar L, Zhang B, Meymand ES, O'Reilly M, Madaj Z, DeWeerd D, Fell MJ, Lee VMY, Bassett DS, Henderson MX. Lubben N, et al. Among authors: henderson mx. Transl Neurodegener. 2024 Mar 4;13(1):13. doi: 10.1186/s40035-024-00403-2. Transl Neurodegener. 2024. PMID: 38438877 Free PMC article.

2

Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies.

Henderson MX, Chung CH, Riddle DM, Zhang B, Gathagan RJ, Seeholzer SH, Trojanowski JQ, Lee VMY. Henderson MX, et al. J Neurosci. 2017 Jun 14;37(24):5870-5884. doi: 10.1523/JNEUROSCI.2705-16.2017. Epub 2017 May 18. J Neurosci. 2017. PMID: 28522732 Free PMC article.

3

LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons.

Henderson MX, Peng C, Trojanowski JQ, Lee VMY. Henderson MX, et al. Acta Neuropathol Commun. 2018 May 31;6(1):45. doi: 10.1186/s40478-018-0550-0. Acta Neuropathol Commun. 2018. PMID: 29855356 Free PMC article.

4

LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic mice.

Henderson MX, Sengupta M, McGeary I, Zhang B, Olufemi MF, Brown H, Trojanowski JQ, Lee VMY. Henderson MX, et al. Acta Neuropathol Commun. 2019 Feb 26;7(1):28. doi: 10.1186/s40478-019-0679-5. Acta Neuropathol Commun. 2019. PMID: 30808409 Free PMC article.

5

α-Synuclein pathology in Parkinson's disease and related α-synucleinopathies.

Henderson MX, Trojanowski JQ, Lee VM. Henderson MX, et al. Neurosci Lett. 2019 Sep 14;709:134316. doi: 10.1016/j.neulet.2019.134316. Epub 2019 Jun 3. Neurosci Lett. 2019. PMID: 31170426 Free PMC article. Review.

6

Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis.

Henderson MX, Cornblath EJ, Darwich A, Zhang B, Brown H, Gathagan RJ, Sandler RM, Bassett DS, Trojanowski JQ, Lee VMY. Henderson MX, et al. Nat Neurosci. 2019 Aug;22(8):1248-1257. doi: 10.1038/s41593-019-0457-5. Epub 2019 Jul 25. Nat Neurosci. 2019. PMID: 31346295 Free PMC article.

7

Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease.

Henderson MX, Sengupta M, Trojanowski JQ, Lee VMY. Henderson MX, et al. Acta Neuropathol Commun. 2019 Nov 16;7(1):183. doi: 10.1186/s40478-019-0836-x. Acta Neuropathol Commun. 2019. PMID: 31733655 Free PMC article.

8

Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease.

Henderson MX, Covell DJ, Chung CH, Pitkin RM, Sandler RM, Decker SC, Riddle DM, Zhang B, Gathagan RJ, James MJ, Trojanowski JQ, Brunden KR, Lee VMY, Luk KC. Henderson MX, et al. Neurobiol Dis. 2020 Mar;136:104712. doi: 10.1016/j.nbd.2019.104712. Epub 2019 Dec 16. Neurobiol Dis. 2020. PMID: 31837422 Free PMC article.

9

Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult.

Henderson MX, Sedor S, McGeary I, Cornblath EJ, Peng C, Riddle DM, Li HL, Zhang B, Brown HJ, Olufemi MF, Bassett DS, Trojanowski JQ, Lee VMY. Henderson MX, et al. Neuron. 2020 Mar 4;105(5):822-836.e7. doi: 10.1016/j.neuron.2019.12.004. Epub 2019 Dec 30. Neuron. 2020. PMID: 31899072 Free PMC article.

10

LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons.

Henderson MX, Changolkar L, Trojanowski JQ, Lee VMY. Henderson MX, et al. J Parkinsons Dis. 2021;11(3):1187-1196. doi: 10.3233/JPD-212562. J Parkinsons Dis. 2021. PMID: 33720852 Free PMC article.

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