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Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis.
Seong CS, Huang C, Boese AC, Hou Y, Koo J, Mouw JK, Rupji M, Joseph G, Johnston HR, Claussen H, Switchenko JM, Behera M, Churchman M, Kolesar JM, Arnold SM, Kerrigan K, Akerley W, Colman H, Johns MA, Arciero C, Zhou W, Marcus AI, Ramalingam SS, Fu H, Gilbert-Ross M. Seong CS, et al. Among authors: claussen h. bioRxiv [Preprint]. 2023 Jan 27:2023.01.26.525772. doi: 10.1101/2023.01.26.525772. bioRxiv. 2023. PMID: 36747658 Free PMC article. Preprint.
Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer.
Koo J, Seong CS, Parker RE, Dwivedi B, Arthur RA, Dinasarapu AR, Johnston HR, Claussen H, Tucker-Burden C, Ramalingam SS, Fu H, Zhou W, Marcus AI, Gilbert-Ross M. Koo J, et al. Among authors: claussen h. bioRxiv [Preprint]. 2023 Jun 14:2023.06.14.544941. doi: 10.1101/2023.06.14.544941. bioRxiv. 2023. Update in: Cancer Res. 2024 Nov 15;84(22):3761-3771. doi: 10.1158/0008-5472.CAN-23-2631. PMID: 37398244 Free PMC article. Updated. Preprint.
mRNA-encoded Cas13 can be used to treat dengue infections in mice.
Basu M, Zurla C, Auroni TT, Vanover D, Chaves LCS, Sadhwani H, Pathak H, Basu R, Beyersdorf JP, Amuda OO, Elsharkawy A, Mosur V, Arthur RA, Claussen H, Sasser LE, Wroe JA, Peck HE, Kumar M, Brinton MA, Santangelo PJ. Basu M, et al. Among authors: claussen h. Nat Microbiol. 2024 Aug;9(8):2160-2172. doi: 10.1038/s41564-024-01726-6. Epub 2024 Jun 5. Nat Microbiol. 2024. PMID: 38839984
mRNA-encoded Cas13 treatment of Influenza via site-specific degradation of genomic RNA.
Chaves LCS, Orr-Burks N, Vanover D, Mosur VV, Hosking SR, Kumar E K P, Jeong H, Jung Y, Assumpção JAF, Peck HE, Nelson SL, Burke KN, Garrison MA, Arthur RA, Claussen H, Heaton NS, Lafontaine ER, Hogan RJ, Zurla C, Santangelo PJ. Chaves LCS, et al. Among authors: claussen h. PLoS Pathog. 2024 Jul 5;20(7):e1012345. doi: 10.1371/journal.ppat.1012345. eCollection 2024 Jul. PLoS Pathog. 2024. PMID: 38968329 Free PMC article.
Circulating short chain fatty acids and fatigue in patients with head and neck cancer: A longitudinal prospective study.
Xiao C, Fedirko V, Claussen H, Richard Johnston H, Peng G, Paul S, Maner-Smith KM, Higgins KA, Shin DM, Saba NF, Wommack EC, Bruner DW, Miller AH. Xiao C, et al. Among authors: claussen h. Brain Behav Immun. 2023 Oct;113:432-443. doi: 10.1016/j.bbi.2023.07.025. Epub 2023 Aug 4. Brain Behav Immun. 2023. PMID: 37543249 Free PMC article.
32 results