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Human cell surface-AAV interactomes identify LRP6 as blood-brain barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder.
Shay TF, Jang S, Brittain TJ, Chen X, Walker B, Tebbutt C, Fan Y, Wolfe DA, Arokiaraj CM, Sullivan EE, Ding X, Wang TY, Lei Y, Chuapoco MR, Chou TF, Gradinaru V. Shay TF, et al. Among authors: gradinaru v. Nat Commun. 2024 Sep 8;15(1):7853. doi: 10.1038/s41467-024-52149-0. Nat Commun. 2024. PMID: 39245720 Free PMC article.
Peripheral neuronal activation shapes the microbiome and alters gut physiology.
Griffiths JA, Yoo BB, Thuy-Boun P, Cantu VJ, Weldon KC, Challis C, Sweredoski MJ, Chan KY, Thron TM, Sharon G, Moradian A, Humphrey G, Zhu Q, Shaffer JP, Wolan DW, Dorrestein PC, Knight R, Gradinaru V, Mazmanian SK. Griffiths JA, et al. Among authors: gradinaru v. Cell Rep. 2024 Apr 23;43(4):113953. doi: 10.1016/j.celrep.2024.113953. Epub 2024 Mar 21. Cell Rep. 2024. PMID: 38517896 Free PMC article.
169 results