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Page 1
Beyond leukotriene formation-The noncanonical functions of 5-lipoxygenase.
Häfner AK, Kahnt AS, Steinhilber D. Häfner AK, et al. Among authors: kahnt as. Prostaglandins Other Lipid Mediat. 2019 Jun;142:24-32. doi: 10.1016/j.prostaglandins.2019.03.003. Epub 2019 Mar 28. Prostaglandins Other Lipid Mediat. 2019. PMID: 30930090 Free article. Review.
Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
Lehmann C, Homann J, Ball AK, Blöcher R, Kleinschmidt TK, Basavarajappa D, Angioni C, Ferreirós N, Häfner AK, Rådmark O, Proschak E, Haeggström JZ, Geisslinger G, Parnham MJ, Steinhilber D, Kahnt AS. Lehmann C, et al. Among authors: kahnt as. FASEB J. 2015 Dec;29(12):5029-43. doi: 10.1096/fj.15-275487. Epub 2015 Aug 19. FASEB J. 2015. PMID: 26289316
Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.
Ball AK, Beilstein K, Wittmann S, Sürün D, Saul MJ, Schnütgen F, Flamand N, Capelo R, Kahnt AS, Frey H, Schaefer L, Marschalek R, Häfner AK, Steinhilber D. Ball AK, et al. Among authors: kahnt as. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):561-571. doi: 10.1016/j.bbalip.2017.02.015. Epub 2017 Feb 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28257804
Long-term stimulation of toll-like receptor-2 and -4 upregulates 5-LO and 15-LO-2 expression thereby inducing a lipid mediator shift in human monocyte-derived macrophages.
Ebert R, Cumbana R, Lehmann C, Kutzner L, Toewe A, Ferreirós N, Parnham MJ, Schebb NH, Steinhilber D, Kahnt AS. Ebert R, et al. Among authors: kahnt as. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158702. doi: 10.1016/j.bbalip.2020.158702. Epub 2020 Mar 25. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32222425 Free article.
On the biosynthesis of specialized pro-resolving mediators in human neutrophils and the influence of cell integrity.
Mainka M, George S, Angioni C, Ebert R, Goebel T, Kampschulte N, Krommes A, Weigert A, Thomas D, Schebb NH, Steinhilber D, Kahnt AS. Mainka M, et al. Among authors: kahnt as. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Mar;1867(3):159093. doi: 10.1016/j.bbalip.2021.159093. Epub 2021 Dec 21. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 34942381 Free article.
Inhibitors of Human 5-Lipoxygenase Potently Interfere With Prostaglandin Transport.
Kahnt AS, Angioni C, Göbel T, Hofmann B, Roos J, Steinbrink SD, Rörsch F, Thomas D, Geisslinger G, Zacharowski K, Grösch S, Steinhilber D, Maier TJ. Kahnt AS, et al. Front Pharmacol. 2022 Jan 21;12:782584. doi: 10.3389/fphar.2021.782584. eCollection 2021. Front Pharmacol. 2022. PMID: 35126121 Free PMC article.
Formation of lipoxins and resolvins in human leukocytes.
Kahnt AS, Schebb NH, Steinhilber D. Kahnt AS, et al. Prostaglandins Other Lipid Mediat. 2023 Jun;166:106726. doi: 10.1016/j.prostaglandins.2023.106726. Epub 2023 Mar 4. Prostaglandins Other Lipid Mediat. 2023. PMID: 36878381 Free article. Review.
Molecular pharmacological profile of a novel thiazolinone-based direct and selective 5-lipoxygenase inhibitor.
Hofmann B, Rödl CB, Kahnt AS, Maier TJ, Michel AA, Hoffmann M, Rau O, Awwad K, Pellowska M, Wurglics M, Wacker M, Zivković A, Fleming I, Schubert-Zsilavecz M, Stark H, Schneider G, Steinhilber D. Hofmann B, et al. Among authors: kahnt as. Br J Pharmacol. 2012 Apr;165(7):2304-13. doi: 10.1111/j.1476-5381.2011.01707.x. Br J Pharmacol. 2012. PMID: 21955369 Free PMC article.
32 results