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Page 1
A Novel Approach for Glioblastoma Treatment by Combining Apoptosis Inducers (TMZ, MTX, and Cytarabine) with E.V.A. (Eltanexor, Venetoclax, and A1210477) Inhibiting XPO1, Bcl-2, and Mcl-1.
Zhao K, Braun M, Meyer L, Otte K, Raifer H, Helmprobst F, Möschl V, Pagenstecher A, Urban H, Ronellenfitsch MW, Steinbach JP, Pesek J, Watzer B, Nockher WA, Taudte RV, Neubauer A, Nimsky C, Bartsch JW, Rusch T. Zhao K, et al. Among authors: nockher wa. Cells. 2024 Apr 4;13(7):632. doi: 10.3390/cells13070632. Cells. 2024. PMID: 38607071 Free PMC article.
Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment.
Sommerfeld L, Knuth I, Finkernagel F, Pesek J, Nockher WA, Jansen JM, Wagner U, Nist A, Stiewe T, Müller-Brüsselbach S, Müller R, Reinartz S. Sommerfeld L, et al. Among authors: nockher wa. Cancers (Basel). 2022 Dec 13;14(24):6154. doi: 10.3390/cancers14246154. Cancers (Basel). 2022. PMID: 36551640 Free PMC article.
Clostridium sporogenes-derived metabolites protect mice against colonic inflammation.
Krause FF, Mangold KI, Ruppert AL, Leister H, Hellhund-Zingel A, Lopez Krol A, Pesek J, Watzer B, Winterberg S, Raifer H, Binder K, Kinscherf R, Walker A, Nockher WA, Taudte RV, Bertrams W, Schmeck B, Kühl AA, Siegmund B, Romero R, Luu M, Göttig S, Bekeredjian-Ding I, Steinhoff U, Schütz B, Visekruna A. Krause FF, et al. Among authors: nockher wa. Gut Microbes. 2024 Jan-Dec;16(1):2412669. doi: 10.1080/19490976.2024.2412669. Epub 2024 Oct 14. Gut Microbes. 2024. PMID: 39397690 Free PMC article.
Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK-STAT signaling in macrophages by perturbing lipid raft structures.
Hammoud MK, Dietze R, Pesek J, Finkernagel F, Unger A, Bieringer T, Nist A, Stiewe T, Bhagwat AM, Nockher WA, Reinartz S, Müller-Brüsselbach S, Graumann J, Müller R. Hammoud MK, et al. Among authors: nockher wa. Mol Oncol. 2022 Sep;16(17):3146-3166. doi: 10.1002/1878-0261.13221. Epub 2022 May 4. Mol Oncol. 2022. PMID: 35451191 Free PMC article.
An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products.
de Los Reyes Jiménez M, Lechner A, Alessandrini F, Bohnacker S, Schindela S, Trompette A, Haimerl P, Thomas D, Henkel F, Mourão A, Geerlof A, da Costa CP, Chaker AM, Brüne B, Nüsing R, Jakobsson PJ, Nockher WA, Feige MJ, Haslbeck M, Ohnmacht C, Marsland BJ, Voehringer D, Harris NL, Schmidt-Weber CB, Esser-von Bieren J. de Los Reyes Jiménez M, et al. Among authors: nockher wa. Sci Transl Med. 2020 Apr 22;12(540):eaay0605. doi: 10.1126/scitranslmed.aay0605. Sci Transl Med. 2020. PMID: 32321863
Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice.
Banhos Danneskiold-Samsøe N, Sonne SB, Larsen JM, Hansen AN, Fjære E, Isidor MS, Petersen S, Henningsen J, Severi I, Sartini L, Schober Y, Wolf J, Nockher WA, Wolfrum C, Cinti S, Sina C, Hansen JB, Madsen L, Brix S, Kristiansen K. Banhos Danneskiold-Samsøe N, et al. Among authors: nockher wa. Sci Rep. 2019 Jun 20;9(1):8979. doi: 10.1038/s41598-019-45062-w. Sci Rep. 2019. PMID: 31222118 Free PMC article.
Urinary uromodulin independently predicts end-stage renal disease and rapid kidney function decline in a cohort of chronic kidney disease patients.
Steubl D, Block M, Herbst V, Nockher WA, Schlumberger W, Kemmner S, Bachmann Q, Angermann S, Wen M, Heemann U, Renders L, Garimella PS, Scherberich J. Steubl D, et al. Among authors: nockher wa. Medicine (Baltimore). 2019 May;98(21):e15808. doi: 10.1097/MD.0000000000015808. Medicine (Baltimore). 2019. PMID: 31124979 Free PMC article.
Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment.
Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R. Reinartz S, et al. Among authors: nockher wa. Mol Oncol. 2019 Feb;13(2):185-201. doi: 10.1002/1878-0261.12396. Epub 2018 Nov 15. Mol Oncol. 2019. PMID: 30353652 Free PMC article.
Serum uromodulin-a marker of kidney function and renal parenchymal integrity.
Scherberich JE, Gruber R, Nockher WA, Christensen EI, Schmitt H, Herbst V, Block M, Kaden J, Schlumberger W. Scherberich JE, et al. Among authors: nockher wa. Nephrol Dial Transplant. 2018 Feb 1;33(2):284-295. doi: 10.1093/ndt/gfw422. Nephrol Dial Transplant. 2018. PMID: 28206617 Free PMC article.
50 results