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116 results

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Page 1
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST.
Sprenger HG, Mittenbühler MJ, Sun Y, Van Vranken JG, Schindler S, Jayaraj A, Khetarpal SA, Vargas-Castillo A, Puszynska AM, Spinelli JB, Armani A, Kunchok T, Ryback B, Seo HS, Song K, Sebastian L, O'Young C, Braithwaite C, Dhe-Paganon S, Burger N, Mills EL, Gygi SP, Arthanari H, Chouchani ET, Sabatini DM, Spiegelman BM. Sprenger HG, et al. bioRxiv [Preprint]. 2024 Apr 10:2024.04.10.588849. doi: 10.1101/2024.04.10.588849. bioRxiv. 2024. PMID: 38645260 Free PMC article. Preprint.
A comprehensive landscape of the zinc-regulated human proteome.
Burger N, Mittenbühler MJ, Xiao H, Shin S, Bozi LHM, Wei S, Sprenger HG, Sun Y, Zhu Y, Darabedian N, Petrocelli JJ, Muro PL, Che J, Chouchani ET. Burger N, et al. Among authors: sprenger hg. bioRxiv [Preprint]. 2024 Jan 5:2024.01.04.574225. doi: 10.1101/2024.01.04.574225. bioRxiv. 2024. PMID: 38260676 Free PMC article. Preprint.
Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Liu W, Wang Y, Bozi LHM, Fischer PD, Jedrychowski MP, Xiao H, Wu T, Darabedian N, He X, Mills EL, Burger N, Shin S, Reddy A, Sprenger HG, Tran N, Winther S, Hinshaw SM, Shen J, Seo HS, Song K, Xu AZ, Sebastian L, Zhao JJ, Dhe-Paganon S, Che J, Gygi SP, Arthanari H, Chouchani ET. Liu W, et al. Among authors: sprenger hg. Nature. 2023 Apr;616(7958):790-797. doi: 10.1038/s41586-023-05939-3. Epub 2023 Mar 15. Nature. 2023. PMID: 36921622
Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues.
Mittenbühler MJ, Jedrychowski MP, Van Vranken JG, Sprenger HG, Wilensky S, Dumesic PA, Sun Y, Tartaglia A, Bogoslavski D, A M, Xiao H, Blackmore KA, Reddy A, Gygi SP, Chouchani ET, Spiegelman BM. Mittenbühler MJ, et al. Among authors: sprenger hg. Cell Metab. 2023 Mar 7;35(3):535-549.e7. doi: 10.1016/j.cmet.2022.12.014. Epub 2023 Jan 20. Cell Metab. 2023. PMID: 36681077 Free PMC article.
Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L.
Wani GA, Sprenger HG, Ndoci K, Chandragiri S, Acton RJ, Schatton D, Kochan SMV, Sakthivelu V, Jevtic M, Seeger JM, Müller S, Giavalisco P, Rugarli EI, Motori E, Langer T, Bergami M. Wani GA, et al. Among authors: sprenger hg. Cell Rep. 2022 Feb 15;38(7):110370. doi: 10.1016/j.celrep.2022.110370. Cell Rep. 2022. PMID: 35172139 Free article.
Fumarate is a terminal electron acceptor in the mammalian electron transport chain.
Spinelli JB, Rosen PC, Sprenger HG, Puszynska AM, Mann JL, Roessler JM, Cangelosi AL, Henne A, Condon KJ, Zhang T, Kunchok T, Lewis CA, Chandel NS, Sabatini DM. Spinelli JB, et al. Among authors: sprenger hg. Science. 2021 Dec 3;374(6572):1227-1237. doi: 10.1126/science.abi7495. Epub 2021 Dec 2. Science. 2021. PMID: 34855504 Free PMC article.
Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity.
Sprenger HG, MacVicar T, Bahat A, Fiedler KU, Hermans S, Ehrentraut D, Ried K, Milenkovic D, Bonekamp N, Larsson NG, Nolte H, Giavalisco P, Langer T. Sprenger HG, et al. Nat Metab. 2021 May;3(5):636-650. doi: 10.1038/s42255-021-00385-9. Epub 2021 Apr 26. Nat Metab. 2021. PMID: 33903774 Free PMC article.
Lipid signalling drives proteolytic rewiring of mitochondria by YME1L.
MacVicar T, Ohba Y, Nolte H, Mayer FC, Tatsuta T, Sprenger HG, Lindner B, Zhao Y, Li J, Bruns C, Krüger M, Habich M, Riemer J, Schwarzer R, Pasparakis M, Henschke S, Brüning JC, Zamboni N, Langer T. MacVicar T, et al. Among authors: sprenger hg. Nature. 2019 Nov;575(7782):361-365. doi: 10.1038/s41586-019-1738-6. Epub 2019 Nov 6. Nature. 2019. PMID: 31695197
The Good and the Bad of Mitochondrial Breakups.
Sprenger HG, Langer T. Sprenger HG, et al. Trends Cell Biol. 2019 Nov;29(11):888-900. doi: 10.1016/j.tcb.2019.08.003. Epub 2019 Sep 5. Trends Cell Biol. 2019. PMID: 31495461 Review.
116 results