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Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1.
Ludwig SD, Meksiriporn B, Tan J, Kureshi R, Mishra A, Kaeo KJ, Zhu A, Stavrakis G, Lee SJ, Schodt DJ, Wester MJ, Kumar D, Lidke KA, Cox AL, Dooley HM, Nimmagadda S, Spangler JB. Ludwig SD, et al. Among authors: kureshi r. Cell Chem Biol. 2024 May 16;31(5):1023. doi: 10.1016/j.chembiol.2024.04.011. Epub 2024 Apr 27. Cell Chem Biol. 2024. PMID: 38679021 Free PMC article. No abstract available.
Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1.
Ludwig SD, Meksiriporn B, Tan J, Kureshi R, Mishra A, Kaeo KJ, Zhu A, Stavrakis G, Lee SJ, Schodt DJ, Wester MJ, Kumar D, Lidke KA, Cox AL, Dooley HM, Nimmagadda S, Spangler JB. Ludwig SD, et al. Among authors: kureshi r. Cell Chem Biol. 2024 May 16;31(5):904-919.e11. doi: 10.1016/j.chembiol.2024.02.014. Epub 2024 Mar 27. Cell Chem Biol. 2024. PMID: 38547863
IFNγ is a central node of cancer immune equilibrium.
Walsh MJ, Stump CT, Kureshi R, Lenehan P, Ali LR, Dougan M, Knipe DM, Dougan SK. Walsh MJ, et al. Among authors: kureshi r. Cell Rep. 2023 Mar 28;42(3):112219. doi: 10.1016/j.celrep.2023.112219. Epub 2023 Mar 6. Cell Rep. 2023. PMID: 36881506 Free PMC article.
Pharmacodynamic measures within tumors expose differential activity of PD(L)-1 antibody therapeutics.
Kumar D, Mishra A, Lisok A, Kureshi R, Shelake S, Plyku D, Sen R, Doucet M, De Silva RA, Mease RC, Forde PM, Jaffee EM, Desai P, Ganguly S, Gabrielson E, Vaidya D, Spangler JB, Nimmagadda S. Kumar D, et al. Among authors: kureshi r. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2107982118. doi: 10.1073/pnas.2107982118. Proc Natl Acad Sci U S A. 2021. PMID: 34508005 Free PMC article.