Zhao M - Search Results

1

Novel Isoalantolactone-Based Derivatives as Potent NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.

Zhao M, Ye N, Liu L, Zhang RJ, Li N, Peng J, Cai XY, Jiang XQ, Su KY, Zhang XL, Rao QR, Liu KJ, Deng DX, Peng AH, Tang MH, Chen LJ, Wu WS, Ye HY. Zhao M, et al. J Med Chem. 2024 May 9;67(9):7516-7538. doi: 10.1021/acs.jmedchem.4c00357. Epub 2024 Apr 30. J Med Chem. 2024. PMID: 38686671

2

Flavonoids from the stems of Millettia pachyloba Drake mediate cytotoxic activity through apoptosis and autophagy in cancer cells.

Yan W, Yang J, Tang H, Xue L, Chen K, Wang L, Zhao M, Tang M, Peng A, Long C, Chen X, Ye H, Chen L. Yan W, et al. Among authors: zhao m. J Adv Res. 2019 Jun 21;20:117-127. doi: 10.1016/j.jare.2019.06.002. eCollection 2019 Nov. J Adv Res. 2019. PMID: 31338224 Free PMC article.

3

Anti-inflammatory Ellagitannins from Cleidion brevipetiolatum for the Treatment of Rheumatoid Arthritis.

Zhao M, Yuan X, Pei YH, Ye HY, Peng AH, Tang MH, Guo DL, Deng Y, Chen LJ. Zhao M, et al. J Nat Prod. 2019 Sep 27;82(9):2409-2418. doi: 10.1021/acs.jnatprod.8b00984. Epub 2019 Aug 16. J Nat Prod. 2019. PMID: 31419126

4

Alkaloids from Black Pepper (Piper nigrum L.) Exhibit Anti-Inflammatory Activity in Murine Macrophages by Inhibiting Activation of NF-κB Pathway.

Pei H, Xue L, Tang M, Tang H, Kuang S, Wang L, Ma X, Cai X, Li Y, Zhao M, Peng A, Ye H, Chen L. Pei H, et al. Among authors: zhao m. J Agric Food Chem. 2020 Feb 26;68(8):2406-2417. doi: 10.1021/acs.jafc.9b07754. Epub 2020 Feb 18. J Agric Food Chem. 2020. PMID: 32031370

5

Flavonoids with Inhibitory Effects on NLRP3 Inflammasome Activation from Millettia velutina.

Ma X, Zhao M, Tang MH, Xue LL, Zhang RJ, Liu L, Ni HF, Cai XY, Kuang S, Hong F, Wang L, Chen K, Tang H, Li Y, Peng AH, Yang JH, Pei HY, Ye HY, Chen LJ. Ma X, et al. Among authors: zhao m. J Nat Prod. 2020 Oct 23;83(10):2950-2959. doi: 10.1021/acs.jnatprod.0c00478. Epub 2020 Sep 29. J Nat Prod. 2020. PMID: 32989985

6

Synthesis and evaluation of new compounds bearing 3-(4-aminopiperidin-1-yl)methyl magnolol scaffold as anticancer agents for the treatment of non-small cell lung cancer via targeting autophagy.

Zhao M, Zheng YH, Zhao QY, Zheng W, Yang JH, Pei HY, Liu L, Liu KJ, Xue LL, Deng DX, Wang L, Ma X, Fu SH, Peng AH, Tang MH, Luo YZ, Ye HY, Chen LJ. Zhao M, et al. Among authors: zhao qy. Eur J Med Chem. 2021 Jan 1;209:112922. doi: 10.1016/j.ejmech.2020.112922. Epub 2020 Oct 10. Eur J Med Chem. 2021. PMID: 33069436

7

Exploring the stability of inhibitor binding to SIK2 using molecular dynamics simulation and binding free energy calculation.

Shi M, Zhao M, Wang L, Liu K, Li P, Liu J, Cai X, Chen L, Xu D. Shi M, et al. Among authors: zhao m. Phys Chem Chem Phys. 2021 Jun 16;23(23):13216-13227. doi: 10.1039/d1cp00717c. Phys Chem Chem Phys. 2021. PMID: 34086021

8

Discovery, Optimization, and Evaluation of Quinazolinone Derivatives with Novel Linkers as Orally Efficacious Phosphoinositide-3-Kinase Delta Inhibitors for Treatment of Inflammatory Diseases.

Liu K, Li D, Zheng W, Shi M, Chen Y, Tang M, Yang T, Zhao M, Deng D, Zhang C, Liu J, Yuan X, Yang Z, Chen L. Liu K, et al. Among authors: zhao m. J Med Chem. 2021 Jul 8;64(13):8951-8970. doi: 10.1021/acs.jmedchem.1c00004. Epub 2021 Jun 17. J Med Chem. 2021. PMID: 34138567

9

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect.

Yang J, Yu Y, Li Y, Yan W, Ye H, Niu L, Tang M, Wang Z, Yang Z, Pei H, Wei H, Zhao M, Wen J, Yang L, Ouyang L, Wei Y, Chen Q, Li W, Chen L. Yang J, et al. Among authors: zhao m. Sci Adv. 2021 May 19;7(21):eabg4168. doi: 10.1126/sciadv.abg4168. Print 2021 May. Sci Adv. 2021. PMID: 34138737 Free PMC article.

10

Structure-based design, synthesis and biological evaluation of aminopyrazines as highly potent, selective, and cellularly active allosteric SHP2 inhibitors.

Tang K, Zhao M, Wu YH, Wu Q, Wang S, Dong Y, Yu B, Song Y, Liu HM. Tang K, et al. Among authors: zhao m. Eur J Med Chem. 2022 Feb 15;230:114106. doi: 10.1016/j.ejmech.2022.114106. Epub 2022 Jan 12. Eur J Med Chem. 2022. PMID: 35063735

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