Nuth M - Search Results

1

Potency of a small molecule that targets the molluscum contagiosum virus processivity factor increases when conjugated to a tripeptide.

Guan H, Nuth M, Scott RW, Parker MH, Strobel ED, Reitz AB, Kulp JL 3rd, Ricciardi RP. Guan H, et al. Among authors: nuth m. Antiviral Res. 2024 Jun;226:105899. doi: 10.1016/j.antiviral.2024.105899. Epub 2024 May 3. Antiviral Res. 2024. PMID: 38705201

2

The processivity factor complex of feline herpes virus-1 is a new drug target.

Zhukovskaya NL, Guan H, Saw YL, Nuth M, Ricciardi RP. Zhukovskaya NL, et al. Among authors: nuth m. Antiviral Res. 2015 Mar;115:17-20. doi: 10.1016/j.antiviral.2014.12.013. Epub 2014 Dec 24. Antiviral Res. 2015. PMID: 25542973

3

Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-Terminal tripeptide of the vaccinia D4 processivity factor.

Nuth M, Guan H, Xiao Y, Kulp JL 3rd, Parker MH, Strobel ED, Isaacs SN, Scott RW, Reitz AB, Ricciardi RP. Nuth M, et al. Antiviral Res. 2019 Feb;162:178-185. doi: 10.1016/j.antiviral.2018.12.011. Epub 2018 Dec 20. Antiviral Res. 2019. PMID: 30578797 Free PMC article.

4

A small molecule that targets the processivity factor of molluscum contagiosum virus has therapeutic potential.

Guan H, Nuth M, Isaacs SN, Xiao Y, Scott RW, Parker MH, Strobel ED, Kulp JL 3rd, Bailey TR, Reitz AB, Ricciardi RP. Guan H, et al. Among authors: nuth m. Antiviral Res. 2023 Mar;211:105520. doi: 10.1016/j.antiviral.2022.105520. Epub 2023 Jan 2. Antiviral Res. 2023. PMID: 36603771 Free PMC article.

5

Design of potent poxvirus inhibitors of the heterodimeric processivity factor required for viral replication.

Nuth M, Guan H, Zhukovskaya N, Saw YL, Ricciardi RP. Nuth M, et al. J Med Chem. 2013 Apr 25;56(8):3235-46. doi: 10.1021/jm301735k. Epub 2013 Apr 8. J Med Chem. 2013. PMID: 23527789 Free PMC article.

6

A novel target and approach for identifying antivirals against molluscum contagiosum virus.

Guan H, Nuth M, Zhukovskaya N, Saw YL, Bell E, Isaacs SN, Ricciardi RP. Guan H, et al. Among authors: nuth m. Antimicrob Agents Chemother. 2014 Dec;58(12):7383-9. doi: 10.1128/AAC.03660-14. Epub 2014 Sep 29. Antimicrob Agents Chemother. 2014. PMID: 25267668 Free PMC article.

7

A Conserved Tripeptide Sequence at the C Terminus of the Poxvirus DNA Processivity Factor D4 Is Essential for Protein Integrity and Function.

Nuth M, Guan H, Ricciardi RP. Nuth M, et al. J Biol Chem. 2016 Dec 30;291(53):27087-27097. doi: 10.1074/jbc.M116.761908. Epub 2016 Nov 11. J Biol Chem. 2016. PMID: 27836975 Free PMC article.

8

Herpes Simplex Virus-1 infection in human primary corneal epithelial cells is blocked by a stapled peptide that targets processive DNA synthesis.

Guan H, Nuth M, Lee V, Lin C, Mitchell CH, Lu W, Scott RW, Parker MH, Kulp JL 3rd, Reitz AB, Ricciardi RP. Guan H, et al. Among authors: nuth m. Ocul Surf. 2021 Jan;19:313-321. doi: 10.1016/j.jtos.2020.11.001. Epub 2020 Nov 6. Ocul Surf. 2021. PMID: 33161128 Free PMC article.

9

Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.

Nuth M, Huang L, Saw YL, Schormann N, Chattopadhyay D, Ricciardi RP. Nuth M, et al. J Med Chem. 2011 May 12;54(9):3260-7. doi: 10.1021/jm101554k. Epub 2011 Apr 19. J Med Chem. 2011. PMID: 21438571 Free PMC article.

10

Discovery of a potent cytotoxic agent that promotes G₂/M phase cell cycle arrest and apoptosis in a malignant human pharyngeal squamous carcinoma cell line.

Nuth M, Benakanakere MR, Ricciardi RP. Nuth M, et al. Int J Oncol. 2022 Apr;60(4):41. doi: 10.3892/ijo.2022.5331. Epub 2022 Feb 25. Int J Oncol. 2022. PMID: 35211767 Free PMC article.

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