Siegwart DJ - Search Results

1

Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells.

Lian X, Chatterjee S, Sun Y, Dilliard SA, Moore S, Xiao Y, Bian X, Yamada K, Sung YC, Levine RM, Mayberry K, John S, Liu X, Smith C, Johnson LT, Wang X, Zhang CC, Liu DR, Newby GA, Weiss MJ, Yen JS, Siegwart DJ. Lian X, et al. Among authors: siegwart dj. Nat Nanotechnol. 2024 Sep;19(9):1409-1417. doi: 10.1038/s41565-024-01680-8. Epub 2024 May 23. Nat Nanotechnol. 2024. PMID: 38783058

2

Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing.

Cheng Q, Wei T, Farbiak L, Johnson LT, Dilliard SA, Siegwart DJ. Cheng Q, et al. Among authors: siegwart dj. Nat Nanotechnol. 2020 Apr;15(4):313-320. doi: 10.1038/s41565-020-0669-6. Epub 2020 Apr 6. Nat Nanotechnol. 2020. PMID: 32251383 Free PMC article.

3

Hydrophobic Domain Structure of Linear-Dendritic Poly(ethylene glycol) Lipids Affects RNA Delivery of Lipid Nanoparticles.

Zhou K, Johnson LT, Xiong H, Barrios S, Minnig JT, Yan Y, Abram B, Yu X, Siegwart DJ. Zhou K, et al. Among authors: siegwart dj. Mol Pharm. 2020 May 4;17(5):1575-1585. doi: 10.1021/acs.molpharmaceut.9b01288. Epub 2020 Apr 23. Mol Pharm. 2020. PMID: 32267707

4

Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing.

Wei T, Cheng Q, Min YL, Olson EN, Siegwart DJ. Wei T, et al. Among authors: siegwart dj. Nat Commun. 2020 Jun 26;11(1):3232. doi: 10.1038/s41467-020-17029-3. Nat Commun. 2020. PMID: 32591530 Free PMC article.

5

A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo.

Lee SM, Cheng Q, Yu X, Liu S, Johnson LT, Siegwart DJ. Lee SM, et al. Among authors: siegwart dj. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5848-5853. doi: 10.1002/anie.202013927. Epub 2021 Feb 1. Angew Chem Int Ed Engl. 2021. PMID: 33305471 Free PMC article.

6

Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR-Cas gene editing.

Liu S, Cheng Q, Wei T, Yu X, Johnson LT, Farbiak L, Siegwart DJ. Liu S, et al. Among authors: siegwart dj. Nat Mater. 2021 May;20(5):701-710. doi: 10.1038/s41563-020-00886-0. Epub 2021 Feb 4. Nat Mater. 2021. PMID: 33542471 Free PMC article.

7

All-In-One Dendrimer-Based Lipid Nanoparticles Enable Precise HDR-Mediated Gene Editing In Vivo.

Farbiak L, Cheng Q, Wei T, Álvarez-Benedicto E, Johnson LT, Lee S, Siegwart DJ. Farbiak L, et al. Among authors: siegwart dj. Adv Mater. 2021 Jul;33(30):e2006619. doi: 10.1002/adma.202006619. Epub 2021 Jun 17. Adv Mater. 2021. PMID: 34137093 Free PMC article.

8

Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration.

Yu X, Liu S, Cheng Q, Lee SM, Wei T, Zhang D, Farbiak L, Johnson LT, Wang X, Siegwart DJ. Yu X, et al. Among authors: siegwart dj. Pharmaceutics. 2021 Nov 12;13(11):1914. doi: 10.3390/pharmaceutics13111914. Pharmaceutics. 2021. PMID: 34834329 Free PMC article.

9

Zwitterionic Phospholipidation of Cationic Polymers Facilitates Systemic mRNA Delivery to Spleen and Lymph Nodes.

Liu S, Wang X, Yu X, Cheng Q, Johnson LT, Chatterjee S, Zhang D, Lee SM, Sun Y, Lin TC, Liu JL, Siegwart DJ. Liu S, et al. Among authors: siegwart dj. J Am Chem Soc. 2021 Dec 22;143(50):21321-21330. doi: 10.1021/jacs.1c09822. Epub 2021 Dec 8. J Am Chem Soc. 2021. PMID: 34878786 Free PMC article.

10

Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA).

Álvarez-Benedicto E, Farbiak L, Márquez Ramírez M, Wang X, Johnson LT, Mian O, Guerrero ED, Siegwart DJ. Álvarez-Benedicto E, et al. Among authors: siegwart dj. Biomater Sci. 2022 Jan 18;10(2):549-559. doi: 10.1039/d1bm01454d. Biomater Sci. 2022. PMID: 34904974 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

77 results

Search Page

Filters