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Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells.
Lian X, Chatterjee S, Sun Y, Dilliard SA, Moore S, Xiao Y, Bian X, Yamada K, Sung YC, Levine RM, Mayberry K, John S, Liu X, Smith C, Johnson LT, Wang X, Zhang CC, Liu DR, Newby GA, Weiss MJ, Yen JS, Siegwart DJ. Lian X, et al. Among authors: sung yc. Nat Nanotechnol. 2024 Sep;19(9):1409-1417. doi: 10.1038/s41565-024-01680-8. Epub 2024 May 23. Nat Nanotechnol. 2024. PMID: 38783058
The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles.
Dilliard SA, Sun Y, Brown MO, Sung YC, Chatterjee S, Farbiak L, Vaidya A, Lian X, Wang X, Lemoff A, Siegwart DJ. Dilliard SA, et al. Among authors: sung yc. J Control Release. 2023 Sep;361:361-372. doi: 10.1016/j.jconrel.2023.07.058. Epub 2023 Aug 10. J Control Release. 2023. PMID: 37536547 Free PMC article.
In vivo editing of lung stem cells for durable gene correction in mice.
Sun Y, Chatterjee S, Lian X, Traylor Z, Sattiraju SR, Xiao Y, Dilliard SA, Sung YC, Kim M, Lee SM, Moore S, Wang X, Zhang D, Wu S, Basak P, Wang J, Liu J, Mann RJ, LePage DF, Jiang W, Abid S, Hennig M, Martinez A, Wustman BA, Lockhart DJ, Jain R, Conlon RA, Drumm ML, Hodges CA, Siegwart DJ. Sun Y, et al. Among authors: sung yc. Science. 2024 Jun 14;384(6701):1196-1202. doi: 10.1126/science.adk9428. Epub 2024 Jun 13. Science. 2024. PMID: 38870301
Combination of induced pluripotent stem cell-derived motor neuron progenitor cells with irradiated brain-derived neurotrophic factor over-expressing engineered mesenchymal stem cells enhanced restoration of axonal regeneration in a chronic spinal cord injury rat model.
Kim JW, Kim J, Lee SM, Rim YA, Sung YC, Nam Y, Kim HJ, Kim H, Jung SI, Lim J, Ju JH. Kim JW, et al. Among authors: sung yc. Stem Cell Res Ther. 2024 Jun 18;15(1):173. doi: 10.1186/s13287-024-03770-9. Stem Cell Res Ther. 2024. PMID: 38886817 Free PMC article.
247 results