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Anandamide is an Early Blood Biomarker of Hermansky-Pudlak Syndrome Pulmonary Fibrosis.
Cinar R, Basu A, Arif M, Park JK, Zawatsky CN, Zuo BLG, Zuo MXG, O'Brien KJ, Behan M, Introne W, Iyer MR, Gahl WA, Malicdan MCV, Gochuico BR. Cinar R, et al. Among authors: zawatsky cn. medRxiv [Preprint]. 2024 May 17:2024.05.16.24307300. doi: 10.1101/2024.05.16.24307300. medRxiv. 2024. PMID: 38798603 Free PMC article. Preprint.
In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis.
Padilha EC, Yang M, Shah P, Wang AQ, Duan J, Park JK, Zawatsky CN, Malicdan MCV, Kunos G, Iyer MR, Gaucher G, Ravenelle F, Cinar R, Xu X. Padilha EC, et al. Among authors: zawatsky cn. Biomed Pharmacother. 2023 Dec;168:115178. doi: 10.1016/j.biopha.2023.115178. Epub 2023 Oct 25. Biomed Pharmacother. 2023. PMID: 37890204 Free PMC article.
Synthesis, Biological Evaluation, and Molecular Modeling Studies of 3,4-Diarylpyrazoline Series of Compounds as Potent, Nonbrain Penetrant Antagonists of Cannabinoid-1 (CB1R) Receptor with Reduced Lipophilicity.
Iyer MR, Cinar R, Wood CM, Zawatsky CN, Coffey NJ, Kim KA, Liu Z, Katz A, Abdalla J, Hassan SA, Lee YS. Iyer MR, et al. Among authors: zawatsky cn. J Med Chem. 2022 Feb 10;65(3):2374-2387. doi: 10.1021/acs.jmedchem.1c01836. Epub 2022 Jan 27. J Med Chem. 2022. PMID: 35084860
CB1 R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky-Pudlak syndrome.
Cinar R, Park JK, Zawatsky CN, Coffey NJ, Bodine SP, Abdalla J, Yokoyama T, Jourdan T, Jay L, Zuo MXG, O'Brien KJ, Huang J, Mackie K, Alimardanov A, Iyer MR, Gahl WA, Kunos G, Gochuico BR, Malicdan MCV. Cinar R, et al. Among authors: zawatsky cn. Clin Transl Med. 2021 Jul;11(7):e471. doi: 10.1002/ctm2.471. Clin Transl Med. 2021. PMID: 34323400 Free PMC article.
13 results