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Page 1
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy.
Nollet EE, Schuldt M, Sequeira V, Binek A, Pham TV, Schoonvelde SAC, Jansen M, Schomakers BV, van Weeghel M, Vaz FM, Houtkooper RH, Van Eyk JE, Jimenez CR, Michels M, Bedi KC Jr, Margulies KB, Dos Remedios CG, Kuster DWD, van der Velden J. Nollet EE, et al. Circ Genom Precis Med. 2024 Jun;17(3):e004369. doi: 10.1161/CIRCGEN.123.004369. Epub 2024 Jun 10. Circ Genom Precis Med. 2024. PMID: 38853772 Free PMC article.
Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration.
Nollet EE, Duursma I, Rozenbaum A, Eggelbusch M, Wüst RCI, Schoonvelde SAC, Michels M, Jansen M, van der Wel NN, Bedi KC, Margulies KB, Nirschl J, Kuster DWD, van der Velden J. Nollet EE, et al. Eur Heart J. 2023 Apr 1;44(13):1170-1185. doi: 10.1093/eurheartj/ehad028. Eur Heart J. 2023. PMID: 36734059 Free PMC article.
The Cardioprotective Effects of Semaglutide Exceed Those of Dietary Weight Loss in Mice With HFpEF.
Withaar C, Meems LMG, Nollet EE, Schouten EM, Schroeder MA, Knudsen LB, Niss K, Madsen CT, Hoegl A, Mazzoni G, van der Velden J, Lam CSP, Silljé HHW, de Boer RA. Withaar C, et al. Among authors: nollet ee. JACC Basic Transl Sci. 2023 Jul 26;8(10):1298-1314. doi: 10.1016/j.jacbts.2023.05.012. eCollection 2023 Oct. JACC Basic Transl Sci. 2023. PMID: 38094687 Free PMC article.
A safety screening platform for individualized cardiotoxicity assessment.
Schwach V, Slaats RH, Cofiño-Fabres C, Ten Den SA, Rivera-Arbeláez JM, Dannenberg M, van Boheemen C, Ribeiro MC, van der Zanden SY, Nollet EE, van der Velden J, Neefjes J, Cao L, Passier R. Schwach V, et al. Among authors: nollet ee. iScience. 2024 Feb 6;27(3):109139. doi: 10.1016/j.isci.2024.109139. eCollection 2024 Mar 15. iScience. 2024. PMID: 38384853 Free PMC article.
SUMOylation does not affect cardiac troponin I stability but alters indirectly the development of force in response to Ca2.
Fertig B, Ling J, Nollet EE, Dobi S, Busiau T, Ishikawa K, Yamada K, Lee A, Kho C, Wills L, Tibbo AJ, Scott M, Grant K, Campbell KS, Birks EJ, MacQuaide N, Hajjar R, Smith GL, van der Velden J, Baillie GS. Fertig B, et al. Among authors: nollet ee. FEBS J. 2022 Oct;289(20):6267-6285. doi: 10.1111/febs.16537. Epub 2022 Jun 8. FEBS J. 2022. PMID: 35633070 Free PMC article.
The IRAK-M death domain: a tale of three surfaces.
Gürkan B, Poelman H, Pereverzeva L, Kruijswijk D, de Vos AF, Groenen AG, Nollet EE, Wichapong K, Lutgens E, van der Poll T, Du J, Wiersinga WJ, Nicolaes GAF, van 't Veer C. Gürkan B, et al. Among authors: nollet ee. Front Mol Biosci. 2024 Jan 10;10:1265455. doi: 10.3389/fmolb.2023.1265455. eCollection 2023. Front Mol Biosci. 2024. PMID: 38268724 Free PMC article.
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