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The multifunction Coxiella effector Vice stimulates macropinocytosis and interferes with the ESCRT machinery.
Bienvenu A, Burette M, Cantet F, Gourdelier M, Swain J, Cazevieille C, Clemente T, Sadi A, Dupont C, Le Fe M, Bonetto N, Bordignon B, Muriaux D, Gilk S, Bonazzi M, Martinez E. Bienvenu A, et al. Among authors: burette m. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2315481121. doi: 10.1073/pnas.2315481121. Epub 2024 Jun 13. Proc Natl Acad Sci U S A. 2024. PMID: 38870060
The secreted protein kinase CstK from Coxiella burnetii influences vacuole development and interacts with the GTPase-activating host protein TBC1D5.
Martinez E, Huc-Brandt S, Brelle S, Allombert J, Cantet F, Gannoun-Zaki L, Burette M, Martin M, Letourneur F, Bonazzi M, Molle V. Martinez E, et al. Among authors: burette m. J Biol Chem. 2020 May 22;295(21):7391-7403. doi: 10.1074/jbc.RA119.010112. Epub 2020 Apr 17. J Biol Chem. 2020. PMID: 32303638 Free PMC article.