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Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report.
Meade A, Frangou E, Choodari-Oskooei B, Larkin J, Powles T, Stewart GD, Albiges L, Bex A, Choueiri TK, Davis ID, Eisen T, Fielding A, Gedye C, Harrison DJ, Kaplan R, Mulhere S, Nathan P, Patel G, Patel J, Plant H, Ritchie A, Rush H, Shakeshaft C, Stockler MR, Suarez C, Thompson J, Thorogood N, Venugopal B, Parmar MKB. Meade A, et al. Among authors: kaplan r. Contemp Clin Trials Commun. 2024 Oct 18;42:101381. doi: 10.1016/j.conctc.2024.101381. eCollection 2024 Dec. Contemp Clin Trials Commun. 2024. PMID: 39555240 Free PMC article.
Inclusivity in fNIRS Studies: Quantifying the Impact of Hair and Skin Characteristics on Signal Quality with Practical Recommendations for Improvement.
Yücel MA, Anderson JE, Rogers D, Hajirahimi P, Farzam P, Gao Y, Kaplan RI, Braun EJ, Muqadam N, Duwadi S, Carlton L, Beeler D, Butler L, Carpenter E, Girnis J, Wilson J, Tripathi V, Zhang Y, Sorger B, von Lühmann A, Somers D, Cronin-Golomb A, Kiran S, Ellis TD, Boas DA. Yücel MA, et al. Among authors: kaplan ri. bioRxiv [Preprint]. 2024 Oct 28:2024.10.28.620644. doi: 10.1101/2024.10.28.620644. bioRxiv. 2024. PMID: 39554177 Free PMC article. Preprint.
Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas.
Borda V, Loesch DP, Guo B, Laboulaye R, Veliz-Otani D, French JN, Leal TP, Gogarten SM, Ikpe S, Gouveia MH, Mendes M, Abecasis GR, Alvim I, Arboleda-Bustos CE, Arboleda G, Arboleda H, Barreto ML, Barwick L, Bezzera MA, Blangero J, Borges V, Caceres O, Cai J, Chana-Cuevas P, Chen Z, Custer B, Dean M, Dinardo C, Domingos I, Duggirala R, Dieguez E, Fernandez W, Ferraz HB, Gilliland F, Guio H, Horta B, Curran JE, Johnsen JM, Kaplan RC, Kelly S, Kenny EE, Konkle BA, Kooperberg C, Lescano A, Lima-Costa MF, Loos RJF, Manichaikul A, Meyers DA, Naslavsky MS, Nickerson DA, North KE, Padilla C, Preuss M, Raggio V, Reiner AP, Rich SS, Rieder CR, Rienstra M, Rotter JI, Rundek T, Sacco RL, Sanchez C, Sankaran VG, Santos-Lobato BL, Schumacher-Schuh AF, Scliar MO, Silverman EK, Sofer T, Lasky-Su J, Tumas V, Weiss ST; Latin American Research Consortium on the Genetics of Parkinson’s Disease (LARGE-PD); National Institute of Neurological Disorders and Stroke (NINDS) Stroke Genetics Network (SiGN) Consortium; Trans-Omics for Precision Medicine (TOPMed) Population Genetics Working Group; Mata IF, Hernandez RD, Tarazona-Santos E, O'Connor TD. Borda V, et al. Among authors: kaplan rc. Cell Genom. 2024 Nov 13;4(11):100692. doi: 10.1016/j.xgen.2024.100692. Epub 2024 Oct 31. Cell Genom. 2024. PMID: 39486408
Identification of allele-specific KIV-2 repeats and impact on Lp(a) measurements for cardiovascular disease risk.
Behera S, Belyeu JR, Chen X, Paulin LF, Nguyen NQH, Newman E, Mahmoud M, Menon VK, Qi Q, Joshi P, Marcovina S, Rossi M, Roller E, Han J, Onuchic V, Avery CL, Ballantyne CM, Rodriguez CJ, Kaplan RC, Muzny DM, Metcalf GA, Gibbs RA, Yu B, Boerwinkle E, Eberle MA, Sedlazeck FJ. Behera S, et al. Among authors: kaplan rc. BMC Med Genomics. 2024 Oct 24;17(1):255. doi: 10.1186/s12920-024-02024-0. BMC Med Genomics. 2024. PMID: 39449055 Free PMC article.
Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma.
Sun NY, Kumar S, Kim YS, Varghese D, Mendoza A, Nguyen R, Okada R, Reilly K, Widemann B, Pommier Y, Elloumi F, Dhall A, Patel M, Aber E, Contreras-Burrola C, Kaplan R, Martinez D, Pogoriler J, Hamilton AK, Diskin SJ, Maris JM, Robey RW, Gottesman MM, Rivero JD, Roper N. Sun NY, et al. Among authors: kaplan r. bioRxiv [Preprint]. 2024 Oct 11:2024.10.09.617077. doi: 10.1101/2024.10.09.617077. bioRxiv. 2024. PMID: 39416174 Free PMC article. Preprint.
To Err Is Human: A Quarter Century of Progress.
Narayan A, Kaplan RM, Adashi EY. Narayan A, et al. Among authors: kaplan rm. J Gen Intern Med. 2024 Oct 7. doi: 10.1007/s11606-024-09087-w. Online ahead of print. J Gen Intern Med. 2024. PMID: 39375317 No abstract available.
Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.
Hawkes G, Beaumont RN, Li Z, Mandla R, Li X, Albert CM, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Boerwinkle E, Brody JA, Carson AP, Chami N, Chen YI, Chung MK, Curran JE, Darbar D, Ellinor PT, Fornage M, Gordeuk VR, Guo X, He J, Hwu CM, Kalyani RR, Kaplan R, Kardia SLR, Kooperberg C, Loos RJF, Lubitz SA, Minster RL, Naseri T, Viali S, Mitchell BD, Murabito JM, Palmer ND, Psaty BM, Redline S, Shoemaker MB, Silverman EK, Telen MJ, Weiss ST, Yanek LR, Zhou H; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Liu CT, North KE, Justice AE, Locke JM, Owens N, Murray A, Patel K, Frayling TM, Wright CF, Wood AR, Lin X, Manning A, Weedon MN. Hawkes G, et al. Among authors: kaplan r. Nat Commun. 2024 Oct 3;15(1):8549. doi: 10.1038/s41467-024-52579-w. Nat Commun. 2024. PMID: 39362880 Free PMC article.
2,639 results