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Page 1
High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells.
Fogarty CL, Nieminen JK, Peräneva L, Lassenius MI, Ahola AJ, Taskinen MR, Jauhiainen M, Kirveskari J, Pussinen P, Hörkkö S, Mäkinen VP, Gordin D, Forsblom C, Groop PH, Vaarala O, Lehto M. Fogarty CL, et al. Among authors: lassenius mi. Acta Diabetol. 2015 Apr;52(2):315-22. doi: 10.1007/s00592-014-0641-8. Epub 2014 Sep 3. Acta Diabetol. 2015. PMID: 25182144
Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
Pedigo CE, Ducasa GM, Leclercq F, Sloan A, Mitrofanova A, Hashmi T, Molina-David J, Ge M, Lassenius MI, Forsblom C, Lehto M, Groop PH, Kretzler M, Eddy S, Martini S, Reich H, Wahl P, Ghiggeri G, Faul C, Burke GW 3rd, Kretz O, Huber TB, Mendez AJ, Merscher S, Fornoni A. Pedigo CE, et al. Among authors: lassenius mi. J Clin Invest. 2016 Sep 1;126(9):3336-50. doi: 10.1172/JCI85939. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482889 Free PMC article.
Cyclin-dependent kinase 2 protects podocytes from apoptosis.
Saurus P, Kuusela S, Dumont V, Lehtonen E, Fogarty CL, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Lehtonen S. Saurus P, et al. Among authors: lassenius mi. Sci Rep. 2016 Feb 15;6:21664. doi: 10.1038/srep21664. Sci Rep. 2016. PMID: 26876672 Free PMC article.
Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway.
Saurus P, Kuusela S, Lehtonen E, Hyvönen ME, Ristola M, Fogarty CL, Tienari J, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Holthöfer H, Lehtonen S. Saurus P, et al. Among authors: lassenius mi. Cell Death Dis. 2015 May 7;6(5):e1752. doi: 10.1038/cddis.2015.125. Cell Death Dis. 2015. PMID: 25950482 Free PMC article.
Intestinal alkaline phosphatase at the crossroad of intestinal health and disease - a putative role in type 1 diabetes.
Lassenius MI, Fogarty CL, Blaut M, Haimila K, Riittinen L, Paju A, Kirveskari J, Järvelä J, Ahola AJ, Gordin D, Härma MA, Kumar A, Hamarneh SR, Hodin RA, Sorsa T, Tervahartiala T, Hörkkö S, Pussinen PJ, Forsblom C, Jauhiainen M, Taskinen MR, Groop PH, Lehto M; FinnDiane Study Group. Lassenius MI, et al. J Intern Med. 2017 Jun;281(6):586-600. doi: 10.1111/joim.12607. Epub 2017 Apr 10. J Intern Med. 2017. PMID: 28393441 Free article.
Cyclodextrin protects podocytes in diabetic kidney disease.
Merscher-Gomez S, Guzman J, Pedigo CE, Lehto M, Aguillon-Prada R, Mendez A, Lassenius MI, Forsblom C, Yoo T, Villarreal R, Maiguel D, Johnson K, Goldberg R, Nair V, Randolph A, Kretzler M, Nelson RG, Burke GW 3rd, Groop PH, Fornoni A; FinnDiane Study Group. Merscher-Gomez S, et al. Among authors: lassenius mi. Diabetes. 2013 Nov;62(11):3817-27. doi: 10.2337/db13-0399. Epub 2013 Jul 8. Diabetes. 2013. PMID: 23835338 Free PMC article.
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