Keillor JW - Search Results

1

Small molecule substrates for the rapid quantification of acyl transfer activity of nylon hydrolase NylC_A.

Rangaswamy AMM, Roy FM, Keillor JW. Rangaswamy AMM, et al. Among authors: keillor jw. Anal Biochem. 2024 Oct;693:115598. doi: 10.1016/j.ab.2024.115598. Epub 2024 Jul 2. Anal Biochem. 2024. PMID: 38964700

2

Targeted Genome Mining Facilitates the Discovery of a Promiscuous, Hyperthermostable Amidase from Thermovenabulum Gondwanense with Notable Nylon-Degrading Capacity.

Hoffman ER, Rangaswamy AMM, Cleveland ME, Keillor JW, Howe GW. Hoffman ER, et al. Among authors: keillor jw. Angew Chem Int Ed Engl. 2024 Oct 23:e202414842. doi: 10.1002/anie.202414842. Online ahead of print. Angew Chem Int Ed Engl. 2024. PMID: 39441552

3

Transcriptomics Studies Reveal Functions of Transglutaminase 2 in Breast Cancer Cells Using Membrane Permeable and Impermeable Inhibitors.

Ancona P, Trentini A, Terrazzan A, Grassilli S, Navals P, Gates EWJ, Rosta V, Cervellati C, Bergamini CM, Pignatelli A, Keillor JW, Taccioli C, Bianchi N. Ancona P, et al. Among authors: keillor jw. J Mol Biol. 2024 May 15;436(10):168569. doi: 10.1016/j.jmb.2024.168569. Epub 2024 Apr 10. J Mol Biol. 2024. PMID: 38604527 Free article.

4

Metabolic characterisation of transglutaminase 2 inhibitor effects in breast cancer cell lines.

Gallo M, Ferrari E, Terrazzan A, Brugnoli F, Spisni A, Taccioli C, Aguiari G, Trentini A, Volinia S, Keillor JW, Bergamini CM, Bianchi N, Pertinhez TA. Gallo M, et al. Among authors: keillor jw. FEBS J. 2023 Nov;290(22):5411-5433. doi: 10.1111/febs.16931. Epub 2023 Aug 29. FEBS J. 2023. PMID: 37597264 Free article.

5

A practical guide for the assay-dependent characterisation of irreversible inhibitors.

Mader LK, Borean JE, Keillor JW. Mader LK, et al. Among authors: keillor jw. RSC Med Chem. 2024 Nov 1. doi: 10.1039/d4md00707g. Online ahead of print. RSC Med Chem. 2024. PMID: 39526224 Free PMC article. Review.

6

Enabling Unfavorable Hydroamination Reactions Using a Chemoselective N-O Bond Reduction.

Ly HM, Almeneim H, Gill MA, Keillor JW, Beauchemin AM. Ly HM, et al. Among authors: keillor jw. Org Lett. 2024 Nov 7. doi: 10.1021/acs.orglett.4c03688. Online ahead of print. Org Lett. 2024. PMID: 39508520

7

Structurally Minimalized and Druglike TGase2 Inhibitors Based on 7-Aminoquinoline-5,8-dione Scaffolds for the Treatment of Diabetic Retinopathy.

Kang J, Jeon HY, Lee J, Bae S, Park GY, Min KJ, Joo J, Lee AJ, Kim HJ, Im CY, Kim EB, Lee JH, Hwang JS, Lee S, Lee JY, Navals P, Keillor JW, Ha KS, Song M. Kang J, et al. Among authors: keillor jw. J Med Chem. 2024 Nov 14;67(21):19716-19735. doi: 10.1021/acs.jmedchem.4c02081. Epub 2024 Oct 24. J Med Chem. 2024. PMID: 39445793

8

Fitting of k_inact and K_I Values from Endpoint Pre-incubation IC₅₀ Data.

Mader LK, Keillor JW. Mader LK, et al. Among authors: keillor jw. ACS Med Chem Lett. 2024 Apr 4;15(5):731-738. doi: 10.1021/acsmedchemlett.4c00054. eCollection 2024 May 9. ACS Med Chem Lett. 2024. PMID: 38746886

9

Conformational Modulation of Tissue Transglutaminase via Active Site Thiol Alkylating Agents: Size Does Not Matter.

Navals P, Rangaswamy AMM, Kasyanchyk P, Berezovski MV, Keillor JW. Navals P, et al. Among authors: keillor jw. Biomolecules. 2024 Apr 19;14(4):496. doi: 10.3390/biom14040496. Biomolecules. 2024. PMID: 38672511 Free PMC article.

10

Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation.

Delgado T, Emerson J, Hong M, Keillor JW, Johnson GV. Delgado T, et al. Among authors: keillor jw. bioRxiv [Preprint]. 2024 Nov 11:2024.04.15.589192. doi: 10.1101/2024.04.15.589192. bioRxiv. 2024. PMID: 38659783 Free PMC article. Preprint.

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