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Page 1
Involvement of Kindlin-1 in cutaneous squamous cell carcinoma.
Carrasco G, Stavrou I, Treanor-Taylor M, Beetham H, Lee M, Masalmeh R, Carreras-Soldevila A, Hardman D, Bernabeu MO, von Kriegsheim A, Inman GJ, Byron A, Brunton VG. Carrasco G, et al. Among authors: beetham h. Oncogenesis. 2024 Jul 9;13(1):24. doi: 10.1038/s41389-024-00526-1. Oncogenesis. 2024. PMID: 38982038 Free PMC article.
A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells.
Hall J, Daniszewski M, Cheung S, Shobhana K, Kumar H, Liang HH, Beetham H, Cho E, Abbott C, Hewitt AW, Simpson KJ, Guymer RH, Paull D, Pébay A, Lidgerwood GE. Hall J, et al. Among authors: beetham h. SLAS Technol. 2024 Jun;29(3):100106. doi: 10.1016/j.slast.2023.08.006. Epub 2023 Aug 30. SLAS Technol. 2024. PMID: 37657710 Free article.
Loss of Integrin-Linked Kinase Sensitizes Breast Cancer to SRC Inhibitors.
Beetham H, Griffith BGC, Murina O, Loftus AEP, Parry DA, Temps C, Culley J, Muir M, Unciti-Broceta A, Sims AH, Byron A, Brunton VG. Beetham H, et al. Cancer Res. 2022 Feb 15;82(4):632-647. doi: 10.1158/0008-5472.CAN-21-0373. Cancer Res. 2022. PMID: 34921014 Free PMC article.
A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability.
Temps C, Lietha D, Webb ER, Li XF, Dawson JC, Muir M, Macleod KG, Valero T, Munro AF, Contreras-Montoya R, Luque-Ortega JR, Fraser C, Beetham H, Schoenherr C, Lopalco M, Arends MJ, Frame MC, Qian BZ, Brunton VG, Carragher NO, Unciti-Broceta A. Temps C, et al. Among authors: beetham h. Cancer Res. 2021 Nov 1;81(21):5438-5450. doi: 10.1158/0008-5472.CAN-21-0613. Epub 2021 Aug 20. Cancer Res. 2021. PMID: 34417202 Free PMC article.
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards.
Kopczynska M, Unwin H, Pugh RJ, Sharif B, Chandy T, Davies DJ, Shield ME, Purchase DE, Tilley SC, Poacher A, Oliva L, Willis S, Ray IE, Hui JNC, Payne BC, Wardle EF, Andrew F, Chan HMP, Barrington J, Hale J, Hawkins J, Nicholas JK, Wirt LE, Thomas LH, Walker M, Pan MP, Ray T, Asim UH, Maidman V, Atiyah Z, Nasser ZM, Tan ZX, Tan LJP, Szakmany T; Welsh Digital Data Collection Platform collaborators. Kopczynska M, et al. Sci Rep. 2021 Aug 10;11(1):16222. doi: 10.1038/s41598-021-95648-6. Sci Rep. 2021. PMID: 34376757 Free PMC article.
E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.
Godwin TD, Kelly ST, Brew TP, Bougen-Zhukov NM, Single AB, Chen A, Stylianou CE, Harris LD, Currie SK, Telford BJ, Beetham HG, Evans GB, Black MA, Guilford PJ. Godwin TD, et al. Among authors: beetham hg. Gastric Cancer. 2019 Mar;22(2):273-286. doi: 10.1007/s10120-018-0859-1. Epub 2018 Jul 31. Gastric Cancer. 2019. PMID: 30066183 Free PMC article.
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