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Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.
Weidinger S, Illig T, Baurecht H, Irvine AD, Rodriguez E, Diaz-Lacava A, Klopp N, Wagenpfeil S, Zhao Y, Liao H, Lee SP, Palmer CN, Jenneck C, Maintz L, Hagemann T, Behrendt H, Ring J, Nothen MM, McLean WH, Novak N. Weidinger S, et al. Among authors: irvine ad. J Allergy Clin Immunol. 2006 Jul;118(1):214-9. doi: 10.1016/j.jaci.2006.05.004. Epub 2006 Jun 9. J Allergy Clin Immunol. 2006. PMID: 16815158
Fleshing out filaggrin phenotypes.
Irvine AD. Irvine AD. J Invest Dermatol. 2007 Mar;127(3):504-7. doi: 10.1038/sj.jid.5700695. J Invest Dermatol. 2007. PMID: 17299430 Free article.
Filaggrin null alleles are not associated with psoriasis.
Zhao Y, Terron-Kwiatkowski A, Liao H, Lee SP, Allen MH, Hull PR, Campbell LE, Trembath RC, Capon F, Griffiths CE, Burden D, McManus R, Hughes R, Kirby B, Rogers SF, Fitzgerald O, Kane D, Barker JN, Palmer CN, Irvine AD, McLean WH. Zhao Y, et al. Among authors: irvine ad. J Invest Dermatol. 2007 Aug;127(8):1878-82. doi: 10.1038/sj.jid.5700817. Epub 2007 Apr 5. J Invest Dermatol. 2007. PMID: 17410197 Free article.
Filaggrin in atopic dermatitis.
O'Regan GM, Sandilands A, McLean WHI, Irvine AD. O'Regan GM, et al. Among authors: irvine ad. J Allergy Clin Immunol. 2008 Oct;122(4):689-693. doi: 10.1016/j.jaci.2008.08.002. Epub 2008 Sep 5. J Allergy Clin Immunol. 2008. PMID: 18774165 Review.
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming.
Fallon PG, Sasaki T, Sandilands A, Campbell LE, Saunders SP, Mangan NE, Callanan JJ, Kawasaki H, Shiohama A, Kubo A, Sundberg JP, Presland RB, Fleckman P, Shimizu N, Kudoh J, Irvine AD, Amagai M, McLean WH. Fallon PG, et al. Among authors: irvine ad. Nat Genet. 2009 May;41(5):602-8. doi: 10.1038/ng.358. Epub 2009 Apr 6. Nat Genet. 2009. PMID: 19349982 Free PMC article.
328 results