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Page 1
Transcriptome-wide association study and Mendelian randomization in pancreatic cancer identifies susceptibility genes and causal relationships with type 2 diabetes and venous thromboembolism.
Tan MCB, Isom CA, Liu Y, Trégouët DA; INVENT Consortium; Wu L, Zhou D, Gamazon ER. Tan MCB, et al. Among authors: tregouet da. EBioMedicine. 2024 Aug;106:105233. doi: 10.1016/j.ebiom.2024.105233. Epub 2024 Jul 12. EBioMedicine. 2024. PMID: 39002386 Free PMC article.
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stančáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hi… See abstract for full author list ➔ Shungin D, et al. Nature. 2015 Feb 12;518(7538):187-196. doi: 10.1038/nature14132. Nature. 2015. PMID: 25673412 Free PMC article.
A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels.
de Vries PS, Reventun P, Brown MR, Heath AS, Huffman JE, Le NQ, Bebo A, Brody JA, Temprano-Sagrera G, Raffield LM, Ozel AB, Thibord F, Jain D, Lewis JP, Rodriguez BAT, Pankratz N, Taylor KD, Polasek O, Chen MH, Yanek LR, Carrasquilla GD, Marioni RE, Kleber ME, Trégouët DA, Yao J, Li-Gao R, Joshi PK, Trompet S, Martinez-Perez A, Ghanbari M, Howard TE, Reiner AP, Arvanitis M, Ryan KA, Bartz TM, Rudan I, Faraday N, Linneberg A, Ekunwe L, Davies G, Delgado GE, Suchon P, Guo X, Rosendaal FR, Klaric L, Noordam R, van Rooij F, Curran JE, Wheeler MM, Osburn WO, O'Connell JR, Boerwinkle E, Beswick A, Psaty BM, Kolcic I, Souto JC, Becker LC, Hansen T, Doyle MF, Harris SE, Moissl AP, Deleuze JF, Rich SS, van Hylckama Vlieg A, Campbell H, Stott DJ, Soria JM, de Maat MPM, Almasy L, Brody LC, Auer PL, Mitchell BD, Ben-Shlomo Y, Fornage M, Hayward C, Mathias RA, Kilpeläinen TO, Lange LA, Cox SR, März W, Morange PE, Rotter JI, Mook-Kanamori DO, Wilson JF, van der Harst P, Jukema JW, Ikram MA, Blangero J, Kooperberg C, Desch KC, Johnson AD, Sabater-Lleal M, Lowenstein CJ, Smith NL, Morrison AC. de Vries PS, et al. Among authors: tregouet da. Blood. 2024 May 2;143(18):1845-1855. doi: 10.1182/blood.2023021452. Blood. 2024. PMID: 38320121
High risk of long-term recurrence after a first episode of venous thromboembolism during pregnancy or postpartum: the REcurrence after a PrEgnAncy related Thrombosis (REPEAT) Study.
Ibrahim-Kosta M, El Harake S, Leclercq B, De Mari C, Secondi JF, Paoletti E, Suchon P, Benredouane Y, Brunet D, Barthet MC, Bruzelius M, Munsch G, Trégouët DA, Morange PE, Goumidi L, Sarlon-Bartoli G. Ibrahim-Kosta M, et al. Among authors: tregouet da. J Thromb Haemost. 2024 Oct 30:S1538-7836(24)00632-9. doi: 10.1016/j.jtha.2024.09.039. Online ahead of print. J Thromb Haemost. 2024. PMID: 39486690
Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomisation analysis.
Cornish N, Haycock P, Brenner H, Figueiredo JC, Galesloot T, Grant RC; InterLymph consortium; INVENT-MVP consortium; Johansson M, Mariosa D, McKay J, Pai R, Pellatt AJ, Samadder NJ, Shi J, Thibord F, Trégouët DA, Voegele C, Thirlwell C, Mumford A, Langdon R. Cornish N, et al. Among authors: tregouet da. medRxiv [Preprint]. 2023 May 18:2023.05.16.23289792. doi: 10.1101/2023.05.16.23289792. medRxiv. 2023. Update in: Int J Epidemiol. 2024 Feb 1;53(1):dyad170. doi: 10.1093/ije/dyad170. PMID: 37292802 Free PMC article. Updated. Preprint.
Causal relationships between risk of venous thromboembolism and 18 cancers: a bidirectional Mendelian randomization analysis.
Cornish N, Haycock P, Brenner H, Figueiredo JC, Galesloot TE, Grant RC, Johansson M, Mariosa D, McKay J, Pai R, Pellatt AJ, Samadder NJ, Shi J, Thibord F, Trégouët DA, Voegele C, Thirlwell C, Mumford A, Langdon R; InterLymph Consortium, INVENT-MVP Consortium. Cornish N, et al. Among authors: tregouet da. Int J Epidemiol. 2024 Feb 1;53(1):dyad170. doi: 10.1093/ije/dyad170. Int J Epidemiol. 2024. PMID: 38124529 Free PMC article.
Association of LIfestyle for BRAin health risk score (LIBRA) and genetic susceptibility with incident dementia and cognitive decline.
Neuffer J, Wagner M, Moreno E, Le Grand Q, Mishra A, Trégouët DA, Leffondre K, Proust-Lima C, Foubert-Samier A, Berr C, Tzourio C, Helmer C, Debette S, Samieri C. Neuffer J, et al. Among authors: tregouet da. Alzheimers Dement. 2024 Jun;20(6):4250-4259. doi: 10.1002/alz.13801. Epub 2024 May 22. Alzheimers Dement. 2024. PMID: 38775256 Free PMC article.
Four missense genetic variants in CUBN are associated with higher levels of eGFR in non-diabetes but not in diabetes mellitus or its subtypes: A genetic association study in Europeans.
Uglebjerg N, Ahmadizar F, Aly DM, Cañadas-Garre M, Hill C, Naber A, Oddsson A, Singh SS, Smyth L, Trégouët DA, Chaker L, Ghanbari M, Steinthorsdottir V, Ahlqvist E, Hadjadj S, Van Hoek M, Kavousi M, McKnight AJ, Sijbrands EJ, Stefansson K, Simons M, Rossing P, Ahluwalia TS. Uglebjerg N, et al. Among authors: tregouet da. Front Endocrinol (Lausanne). 2023 Feb 28;14:1081741. doi: 10.3389/fendo.2023.1081741. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36926036 Free PMC article.
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease.
Duperron MG, Knol MJ, Le Grand Q, Evans TE, Mishra A, Tsuchida A, Roshchupkin G, Konuma T, Trégouët DA, Romero JR, Frenzel S, Luciano M, Hofer E, Bourgey M, Dueker ND, Delgado P, Hilal S, Tankard RM, Dubost F, Shin J, Saba Y, Armstrong NJ, Bordes C, Bastin ME, Beiser A, Brodaty H, Bülow R, Carrera C, Chen C, Cheng CY, Deary IJ, Gampawar PG, Himali JJ, Jiang J, Kawaguchi T, Li S, Macalli M, Marquis P, Morris Z, Muñoz Maniega S, Miyamoto S, Okawa M, Paradise M, Parva P, Rundek T, Sargurupremraj M, Schilling S, Setoh K, Soukarieh O, Tabara Y, Teumer A, Thalamuthu A, Trollor JN, Valdés Hernández MC, Vernooij MW, Völker U, Wittfeld K, Wong TY, Wright MJ, Zhang J, Zhao W, Zhu YC, Schmidt H, Sachdev PS, Wen W, Yoshida K, Joutel A, Satizabal CL, Sacco RL, Bourque G; CHARGE consortium; Lathrop M, Paus T, Fernandez-Cadenas I, Yang Q, Mazoyer B, Boutinaud P, Okada Y, Grabe HJ, Mather KA, Schmidt R, Joliot M, Ikram MA, Matsuda F, Tzourio C, Wardlaw JM, Seshadri S, Adams HHH, Debette S. Duperron MG, et al. Among authors: tregouet da. Nat Med. 2023 Apr;29(4):950-962. doi: 10.1038/s41591-023-02268-w. Epub 2023 Apr 17. Nat Med. 2023. PMID: 37069360 Free PMC article.
269 results