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In silico gepotidacin target mining among 33 213 global Neisseria gonorrhoeae genomes from 1928 to 2023 combined with gepotidacin MIC testing of 22 gonococcal isolates with different GyrA and ParC substitutions.
David A, Golparian D, Jacobsson S, Stratton C, Lan PT, Shimuta K, Sonnenberg P, Field N, Ohnishi M, Davies C, Unemo M. David A, et al. Among authors: lan pt. J Antimicrob Chemother. 2024 Sep 3;79(9):2221-2226. doi: 10.1093/jac/dkae217. J Antimicrob Chemother. 2024. PMID: 39004438 Free PMC article.
GyrB in silico mining in 27 151 global gonococcal genomes from 1928-2021 combined with zoliflodacin in vitro testing of 71 international gonococcal isolates with different GyrB, ParC and ParE substitutions confirms high susceptibility.
Golparian D, Jacobsson S, Sánchez-Busó L, Bazzo ML, Lan PT, Galarza P, Ohnishi M, Unemo M. Golparian D, et al. Among authors: lan pt. J Antimicrob Chemother. 2022 Dec 23;78(1):150-154. doi: 10.1093/jac/dkac366. J Antimicrob Chemother. 2022. PMID: 36308328 Clinical Trial.
The novel 2024 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations and superseded WHO N. gonorrhoeae reference strains-phenotypic, genetic and reference genome characterization.
Unemo M, Sánchez-Busó L, Golparian D, Jacobsson S, Shimuta K, Lan PT, Eyre DW, Cole M, Maatouk I, Wi T, Lahra MM. Unemo M, et al. Among authors: lan pt. J Antimicrob Chemother. 2024 Aug 1;79(8):1885-1899. doi: 10.1093/jac/dkae176. J Antimicrob Chemother. 2024. PMID: 38889110 Free PMC article.
Interactions between climate change, urban infrastructure and mobility are driving dengue emergence in Vietnam.
Gibb R, Colón-González FJ, Lan PT, Huong PT, Nam VS, Duoc VT, Hung DT, Dong NT, Chien VC, Trang LTT, Kien Quoc D, Hoa TM, Tai NH, Hang TT, Tsarouchi G, Ainscoe E, Harpham Q, Hofmann B, Lumbroso D, Brady OJ, Lowe R. Gibb R, et al. Among authors: lan pt. Nat Commun. 2023 Dec 11;14(1):8179. doi: 10.1038/s41467-023-43954-0. Nat Commun. 2023. PMID: 38081831 Free PMC article.
50 results