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Page 1
Mitochondrial antioxidants abate SARS-COV-2 pathology in mice.
Guarnieri JW, Lie T, Albrecht YES, Hewin P, Jurado KA, Widjaja GA, Zhu Y, McManus MJ, Kilbaugh TJ, Keith K, Potluri P, Taylor D, Angelin A, Murdock DG, Wallace DC. Guarnieri JW, et al. Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2321972121. doi: 10.1073/pnas.2321972121. Epub 2024 Jul 15. Proc Natl Acad Sci U S A. 2024. PMID: 39008677 Free PMC article.
The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection.
McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Sharma S, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Davanzo GG, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM; UNC COVID-19 Pathobiology Consortium; Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Moraes-Vieira PM, Vanderburg C, Wallace DC, Schisler J, Mason CE, Chatterjee A, Meller R, Beheshti A. McDonald JT, et al. Among authors: guarnieri jw. bioRxiv [Preprint]. 2021 Aug 18:2021.04.23.441024. doi: 10.1101/2021.04.23.441024. bioRxiv. 2021. Update in: Cell Rep. 2021 Oct 19;37(3):109839. doi: 10.1016/j.celrep.2021.109839. PMID: 33948587 Free PMC article. Updated. Preprint.
TARGETED DOWN REGULATION OF CORE MITOCHONDRIAL GENES DURING SARS-COV-2 INFECTION.
Guarnieri JW, Dybas JM, Fazelinia H, Kim MS, Frere J, Zhang Y, Albrecht YS, Murdock DG, Angelin A, Singh LN, Weiss SL, Best SM, Lott MT, Cope H, Zaksas V, Saravia-Butler A, Meydan C, Foox J, Mozsary C, Kidane YH, Priebe W, Emmett MR, Meller R, Singh U, Bram Y, tenOever BR, Heise MT, Moorman NJ, Madden EA, Taft-Benz SA, Anderson EJ, Sanders WA, Dickmander RJ, Baxter VK, Baylin SB, Wurtele ES, Moraes-Vieira PM, Taylor D, Mason CE, Schisler JC, Schwartz RE, Beheshti A, Wallace DC. Guarnieri JW, et al. bioRxiv [Preprint]. 2022 Feb 22:2022.02.19.481089. doi: 10.1101/2022.02.19.481089. bioRxiv. 2022. PMID: 35233572 Free PMC article. Preprint.
SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease.
Haltom J, Trovao NS, Guarnieri J, Vincent P, Singh U, Tsoy S, O'Leary CA, Bram Y, Widjaja GA, Cen Z, Meller R, Baylin SB, Moss WN, Nikolau BJ, Enguita FJ, Wallace DC, Beheshti A, Schwartz R, Wurtele ES. Haltom J, et al. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298847. doi: 10.1101/2023.11.27.23298847. medRxiv. 2023. PMID: 38076862 Free PMC article. Preprint.
SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19.
Guarnieri JW, Haltom JA, Albrecht YES, Lie T, Olali AZ, Widjaja GA, Ranshing SS, Angelin A, Murdock D, Wallace DC. Guarnieri JW, et al. Pharmacol Res. 2024 Jun;204:107170. doi: 10.1016/j.phrs.2024.107170. Epub 2024 Apr 12. Pharmacol Res. 2024. PMID: 38614374 Free article. Review.
Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight.
Houerbi N, Kim J, Overbey EG, Batra R, Schweickart A, Patras L, Lucotti S, Ryon KA, Najjar D, Meydan C, Damle N, Chin C, Narayanan SA, Guarnieri JW, Widjaja G, Beheshti A, Tobias G, Vatter F, Hirschberg JW, Kleinman A, Afshin EE, MacKay M, Chen Q, Miller D, Gajadhar AS, Williamson L, Tandel P, Yang Q, Chu J, Benz R, Siddiqui A, Hornburg D, Gross S, Shirah B, Krumsiek J, Mateus J, Mao X, Matei I, Mason CE. Houerbi N, et al. Among authors: guarnieri jw. Nat Commun. 2024 Jun 11;15(1):4862. doi: 10.1038/s41467-024-48841-w. Nat Commun. 2024. PMID: 38862464 Free PMC article.
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs.
McDonald JT, Kim J, Farmerie L, Johnson ML, Trovao NS, Arif S, Siew K, Tsoy S, Bram Y, Park J, Overbey E, Ryon K, Haltom J, Singh U, Enguita FJ, Zaksas V, Guarnieri JW, Topper M, Wallace DC, Meydan C, Baylin S, Meller R, Muratani M, Porterfield DM, Kaufman B, Mori MA, Walsh SB, Sigaudo-Roussel D, Mebarek S, Bottini M, Marquette CA, Wurtele ES, Schwartz RE, Galeano D, Mason CE, Grabham P, Beheshti A. McDonald JT, et al. Among authors: guarnieri jw. Nat Commun. 2024 Jun 11;15(1):4825. doi: 10.1038/s41467-024-48920-y. Nat Commun. 2024. PMID: 38862542 Free PMC article.
PET Imaging with [18F]ROStrace Detects Oxidative Stress and Predicts Parkinson's Disease Progression in Mice.
Zhu Y, Kohli N, Young A, Sheldon M, Coni J, Rajasekaran M, Robinson L, Chroneos R, Riley S, Guarnieri JW, Jose J, Patel N, Wallace DC, Li S, Lee H, Mach RH, McManus MJ. Zhu Y, et al. Among authors: guarnieri jw. Antioxidants (Basel). 2024 Oct 12;13(10):1226. doi: 10.3390/antiox13101226. Antioxidants (Basel). 2024. PMID: 39456479 Free PMC article.
Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine.
Muccilli SG, Schwarz B, Jessop F, Shannon JG, Bohrnsen E, Shue B, Hong SH, Hsu T, Ashbrook AW, Guarnieri JW, Lack J, Wallace DC, Bosio CM, MacDonald MR, Rice CM, Yewdell JW, Best SM. Muccilli SG, et al. Among authors: guarnieri jw. bioRxiv [Preprint]. 2024 Sep 15:2024.09.04.611167. doi: 10.1101/2024.09.04.611167. bioRxiv. 2024. PMID: 39282299 Free PMC article. Preprint.
ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Stojanovic L, Abbotts R, Tripathi K, Coon CM, Rajendran S, Farid EA, Hostetter G, Guarnieri JW, Wallace DC, Liu S, Wan J, Calendo G, Marker R, Gohari Z, Inayatullah MMA, Tiwari VK, Kader T, Santagata S, Drapkin R, Kommoss S, Pfisterer J, Konecny GE, Coopergard R, Issa JP, Winterhoff BJN, Topper MJ, Sandusky GE, Miller KD, Baylin SB, Nephew KP, Rassool FV. Stojanovic L, et al. Among authors: guarnieri jw. bioRxiv [Preprint]. 2024 Oct 21:2024.10.18.618659. doi: 10.1101/2024.10.18.618659. bioRxiv. 2024. PMID: 39484607 Free PMC article. Preprint.
18 results