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Host-directed therapy to combat mycobacterial infections.
Kilinç G, Saris A, Ottenhoff THM, Haks MC. Kilinç G, et al. Among authors: ottenhoff thm. Immunol Rev. 2021 May;301(1):62-83. doi: 10.1111/imr.12951. Epub 2021 Feb 9. Immunol Rev. 2021. PMID: 33565103 Free PMC article. Review.
Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections.
Heemskerk MT, Korbee CJ, Esselink JJ, Dos Santos CC, van Veen S, Gordijn IF, Vrieling F, Walburg KV, Engele CG, Dijkman K, Wilson L, Verreck FAW, Ottenhoff THM, Haks MC. Heemskerk MT, et al. Among authors: ottenhoff thm. Sci Rep. 2021 Oct 4;11(1):19634. doi: 10.1038/s41598-021-98980-z. Sci Rep. 2021. PMID: 34608194 Free PMC article.
Repurposing Tamoxifen as Potential Host-Directed Therapeutic for Tuberculosis.
Boland R, Heemskerk MT, Forn-Cuní G, Korbee CJ, Walburg KV, Esselink JJ, Carvalho Dos Santos C, de Waal AM, van der Hoeven DCM, van der Sar E, de Ries AS, Xie J, Spaink HP, van der Vaart M, Haks MC, Meijer AH, Ottenhoff THM. Boland R, et al. Among authors: ottenhoff thm. mBio. 2023 Feb 28;14(1):e0302422. doi: 10.1128/mbio.03024-22. Epub 2022 Dec 7. mBio. 2023. PMID: 36475748 Free PMC article.
New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles.
Coppola M, van Meijgaarden KE, Franken KL, Commandeur S, Dolganov G, Kramnik I, Schoolnik GK, Comas I, Lund O, Prins C, van den Eeden SJ, Korsvold GE, Oftung F, Geluk A, Ottenhoff TH. Coppola M, et al. Sci Rep. 2016 Nov 28;6:37793. doi: 10.1038/srep37793. Sci Rep. 2016. PMID: 27892960 Free PMC article.
Functional Inhibition of Host Histone Deacetylases (HDACs) Enhances in vitro and in vivo Anti-mycobacterial Activity in Human Macrophages and in Zebrafish.
Moreira JD, Koch BEV, van Veen S, Walburg KV, Vrieling F, Mara Pinto Dabés Guimarães T, Meijer AH, Spaink HP, Ottenhoff THM, Haks MC, Heemskerk MT. Moreira JD, et al. Among authors: ottenhoff thm. Front Immunol. 2020 Feb 3;11:36. doi: 10.3389/fimmu.2020.00036. eCollection 2020. Front Immunol. 2020. PMID: 32117228 Free PMC article.
383 results