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Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its ability to act as a chromatin organizer.
Do C, Jiang G, Cova G, Katsifis CC, Narducci DN, Yang J, Sakellaropoulos T, Vidal R, Lhoumaud P, Tsirigos A, Regis FFD, Kakabadze N, Nora EP, Noyes M, Cheng X, Hansen AS, Skok JA. Do C, et al. Among authors: cheng x. Res Sq [Preprint]. 2024 Jul 19:rs.3.rs-4670379. doi: 10.21203/rs.3.rs-4670379/v1. Res Sq. 2024. PMID: 39070636 Free PMC article. Preprint.
Structures of CTCF-DNA complexes including all 11 zinc fingers.
Yang J, Horton JR, Liu B, Corces VG, Blumenthal RM, Zhang X, Cheng X. Yang J, et al. Among authors: cheng x. Nucleic Acids Res. 2023 Sep 8;51(16):8447-8462. doi: 10.1093/nar/gkad594. Nucleic Acids Res. 2023. PMID: 37439339 Free PMC article.
Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Zhou J, Chen Q, Ren R, Yang J, Liu B, Horton JR, Chang C, Li C, Maksoud L, Yang Y, Rotili D, Jain AK, Zhang X, Blumenthal RM, Chen T, Gao Y, Valente S, Mai A, Cheng X. Zhou J, et al. Among authors: cheng x. Cell Chem Biol. 2024 Oct 14:S2451-9456(24)00403-3. doi: 10.1016/j.chembiol.2024.09.007. Online ahead of print. Cell Chem Biol. 2024. PMID: 39437789 Free article.
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