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273 results

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Page 1
Preclinical Development of a Romidepsin Nanoparticle Demonstrates Superior Tolerability and Efficacy in Models of Human T-Cell Lymphoma and Large Granular Lymphocyte Leukemia.
Pal I, Illendula A, Joyner A, Manavalan JS, Deddens TM, Sabzevari A, Damera DP, Zuberi S, Marchi E, Fox TE, Dunlap-Brown ME, Jayappa KD, Craig JW, Loughran TP, Feith DJ, O'Connor OA. Pal I, et al. Among authors: loughran tp. bioRxiv [Preprint]. 2024 Jul 19:2024.07.18.603379. doi: 10.1101/2024.07.18.603379. bioRxiv. 2024. PMID: 39071370 Free PMC article. Preprint.
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
Ung J, Tan SF, Fox TE, Shaw JJ, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Ung J, et al. Among authors: loughran tp. bioRxiv [Preprint]. 2023 Oct 23:2023.10.21.563437. doi: 10.1101/2023.10.21.563437. bioRxiv. 2023. Update in: Cancers (Basel). 2023 Dec 15;15(24):5866. doi: 10.3390/cancers15245866. PMID: 37961314 Free PMC article. Updated. Preprint.
Acute myeloid leukemia mitochondria hydrolyze ATP to resist chemotherapy.
Hagen JT, Montgomery M, Aruleba R, Chrest B, Green TD, Kassai M, Zeczycki T, Schmidt CA, Bhowmick D, Tan SF, Feith D, Chalfant C, Loughran T, Liles D, Minden M, Schimmer A, Cabot M, McClung J, Fisher-Wellman K. Hagen JT, et al. bioRxiv [Preprint]. 2024 Nov 11:2024.04.12.589110. doi: 10.1101/2024.04.12.589110. bioRxiv. 2024. PMID: 38659944 Free PMC article. Preprint.
Activating STAT3 mutations in CD8+ T-cells correlate to serological positivity in rheumatoid arthritis.
Moosic KB, Olson TL, Freijat M, Khalique S, Hamele CE, Shemo B, Boodoo J, Baker W, Khurana G, Schmachtenberg M, Duffy T, Ratan A, Darrah E, Andrade F, Jones M, Olson KC, Feith DJ, Kimpel DL, Loughran TP Jr. Moosic KB, et al. Among authors: loughran tp jr. Front Immunol. 2024 Oct 21;15:1466276. doi: 10.3389/fimmu.2024.1466276. eCollection 2024. Front Immunol. 2024. PMID: 39497832 Free PMC article.
A modern view of LGL leukemia.
Marchand T, Lamy T, Loughran TP Jr. Marchand T, et al. Among authors: loughran tp jr. Blood. 2024 Oct 31;144(18):1910-1923. doi: 10.1182/blood.2023021790. Blood. 2024. PMID: 38848524 Review.
Plurality Over Parsimony: When Two Diagnoses Are More Likely Than One.
Raghuwanshi JS, Roberts N, Loughran TP Jr, El Chaer F, Girton M, Moulder G. Raghuwanshi JS, et al. Among authors: loughran tp jr. J Gen Intern Med. 2024 May;39(7):1257-1263. doi: 10.1007/s11606-023-08585-7. Epub 2024 Feb 26. J Gen Intern Med. 2024. PMID: 38409513 No abstract available.
A fluorogenic substrate for the detection of lipid amidases in intact cells.
Casasampere M, Ung J, Iñáñez A, Dufau C, Tsuboi K, Casas J, Tan SF, Feith DJ, Andrieu-Abadie N, Segui B, Loughran TP Jr, Abad JL, Fabrias G. Casasampere M, et al. Among authors: loughran tp jr. J Lipid Res. 2024 Mar;65(3):100520. doi: 10.1016/j.jlr.2024.100520. Epub 2024 Feb 17. J Lipid Res. 2024. PMID: 38369184 Free PMC article.
KLRG1 Cell Depletion as a Novel Therapeutic Strategy in Patients with Mature T-Cell Lymphoma Subtypes.
Assatova B, Willim R, Trevisani C, Haskett G, Kariya KM, Chopra K, Park SR, Tolstorukov MY, McCabe SM, Duffy J, Louissaint A Jr, Huuhtanen J, Bhattacharya D, Mustjoki S, Koh MJ, Powers F, Morgan EA, Yang L, Pinckney B, Cotton MJ, Crabbe A, Ziemba JB, Brain I, Heavican-Foral TB, Iqbal J, Nemec R, Rider AB, Ford JG, Koh MJ, Scanlan N, Feith DJ, Loughran TP Jr, Kim WS, Choi J, Roels J, Boehme L, Putteman T, Taghon T, Barnes JA, Johnson PC, Jacobsen ED, Greenberg SA, Weinstock DM, Jain S. Assatova B, et al. Among authors: loughran tp jr. Clin Cancer Res. 2024 Jun 3;30(11):2514-2530. doi: 10.1158/1078-0432.CCR-23-3504. Clin Cancer Res. 2024. PMID: 38252421 Free PMC article.
Acute myeloid leukemia stratifies as 2 clinically relevant sphingolipidomic subtypes.
Paudel BB, Tan SF, Fox TE, Ung J, Golla U, Shaw JJP, Dunton W, Lee I, Fares WA, Patel S, Sharma A, Viny AD, Barth BM, Tallman MS, Cabot M, Garrett-Bakelman FE, Levine RL, Kester M, Feith DJ, Claxton D, Janes KA, Loughran TP Jr. Paudel BB, et al. Among authors: loughran tp jr. Blood Adv. 2024 Mar 12;8(5):1137-1142. doi: 10.1182/bloodadvances.2023010535. Blood Adv. 2024. PMID: 38170742 Free PMC article. No abstract available.
273 results