Zhai P - Search Results

1

Cardiomyocyte senescence and the potential therapeutic role of senolytics in the heart.

Zhai P, Sadoshima J. Zhai P, et al. J Cardiovasc Aging. 2024 Apr;4(2):18. doi: 10.20517/jca.2024.06. Epub 2024 May 30. J Cardiovasc Aging. 2024. PMID: 39119147 Free PMC article.

2

Ser9 phosphorylation of GSK-3β promotes aging in the heart through suppression of autophagy.

Chen Y, Maejima Y, Shirakabe A, Yamamoto T, Ikeda Y, Sadoshima J, Zhai P. Chen Y, et al. Among authors: zhai p. J Cardiovasc Aging. 2021;1:9. doi: 10.20517/jca.2021.13. Epub 2021 Aug 23. J Cardiovasc Aging. 2021. PMID: 34778891 Free PMC article.

3

Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart.

Nah J, Shirakabe A, Mukai R, Zhai P, Sung EA, Ivessa A, Mizushima W, Nakada Y, Saito T, Hu C, Jung YK, Sadoshima J. Nah J, et al. Among authors: zhai p. Cardiovasc Res. 2022 Sep 20;118(12):2638-2651. doi: 10.1093/cvr/cvac003. Cardiovasc Res. 2022. PMID: 35018428 Free PMC article.

4

Suppression of autophagy induces senescence in the heart.

Zhai P, Sung EA, Shiheido-Watanabe Y, Takayama K, Tian Y, Sadoshima J. Zhai P, et al. J Mol Cell Cardiol. 2024 Oct;195:83-96. doi: 10.1016/j.yjmcc.2024.08.001. Epub 2024 Aug 6. J Mol Cell Cardiol. 2024. PMID: 39117176 Free article.

5

Sirt1 regulates aging and resistance to oxidative stress in the heart.

Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF, Sadoshima J. Alcendor RR, et al. Among authors: zhai p. Circ Res. 2007 May 25;100(10):1512-21. doi: 10.1161/01.RES.0000267723.65696.4a. Epub 2007 Apr 19. Circ Res. 2007. PMID: 17446436

6

Nifedipine inhibits cardiac hypertrophy and left ventricular dysfunction in response to pressure overload.

Ago T, Yang Y, Zhai P, Sadoshima J. Ago T, et al. Among authors: zhai p. J Cardiovasc Transl Res. 2010 Aug;3(4):304-13. doi: 10.1007/s12265-010-9182-x. Epub 2010 May 1. J Cardiovasc Transl Res. 2010. PMID: 20559781 Free PMC article.

7

Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion.

Takagi H, Hsu CP, Kajimoto K, Shao D, Yang Y, Maejima Y, Zhai P, Yehia G, Yamada C, Zablocki D, Sadoshima J. Takagi H, et al. Among authors: zhai p. Circ Res. 2010 Sep 3;107(5):642-9. doi: 10.1161/CIRCRESAHA.110.217554. Epub 2010 Jul 1. Circ Res. 2010. PMID: 20595653 Free PMC article.

8

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.

Kuroda J, Ago T, Matsushima S, Zhai P, Schneider MD, Sadoshima J. Kuroda J, et al. Among authors: zhai p. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15565-70. doi: 10.1073/pnas.1002178107. Epub 2010 Aug 16. Proc Natl Acad Sci U S A. 2010. PMID: 20713697 Free PMC article.

9

Oxidative stress stimulates autophagic flux during ischemia/reperfusion.

Hariharan N, Zhai P, Sadoshima J. Hariharan N, et al. Among authors: zhai p. Antioxid Redox Signal. 2011 Jun;14(11):2179-90. doi: 10.1089/ars.2010.3488. Epub 2011 Jan 27. Antioxid Redox Signal. 2011. PMID: 20812860 Free PMC article.

10

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice.

Del Re DP, Matsuda T, Zhai P, Gao S, Clark GJ, Van Der Weyden L, Sadoshima J. Del Re DP, et al. Among authors: zhai p. J Clin Invest. 2010 Oct;120(10):3555-67. doi: 10.1172/JCI43569. Epub 2010 Sep 20. J Clin Invest. 2010. PMID: 20890045 Free PMC article.

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