Wuest WM - Search Results

1

In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe.

Scharnow AM, Solinski AE, Rowe S, Drechsel I, Zhang H, Shaw E, Page JE, Wu H, Sieber SA, Wuest WM. Scharnow AM, et al. Among authors: wuest wm. J Am Chem Soc. 2024 Aug 21;146(33):23449-23456. doi: 10.1021/jacs.4c06658. Epub 2024 Aug 12. J Am Chem Soc. 2024. PMID: 39133525 Free PMC article.

2

Diverted Total Synthesis of Carolacton-Inspired Analogs Yields Three Distinct Phenotypes in Streptococcus mutans Biofilms.

Solinski AE, Koval AB, Brzozowski RS, Morrison KR, Fraboni AJ, Carson CE, Eshraghi AR, Zhou G, Quivey RG Jr, Voelz VA, Buttaro BA, Wuest WM. Solinski AE, et al. Among authors: wuest wm. J Am Chem Soc. 2017 May 31;139(21):7188-7191. doi: 10.1021/jacs.7b03879. Epub 2017 May 17. J Am Chem Soc. 2017. PMID: 28502178 Free PMC article.

3

Honokiol-Inspired Analogs as Inhibitors of Oral Bacteria.

Solinski AE, Ochoa C, Lee YE, Paniak T, Kozlowski MC, Wuest WM. Solinski AE, et al. Among authors: wuest wm. ACS Infect Dis. 2018 Feb 9;4(2):118-122. doi: 10.1021/acsinfecdis.7b00178. Epub 2017 Dec 13. ACS Infect Dis. 2018. PMID: 29236466 Free PMC article.

4

Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.

Keohane CE, Steele AD, Fetzer C, Khowsathit J, Van Tyne D, Moynié L, Gilmore MS, Karanicolas J, Sieber SA, Wuest WM. Keohane CE, et al. Among authors: wuest wm. J Am Chem Soc. 2018 Feb 7;140(5):1774-1782. doi: 10.1021/jacs.7b11212. Epub 2018 Jan 24. J Am Chem Soc. 2018. PMID: 29300464 Free PMC article.

5

Dual Inhibitor of Staphylococcus aureus Virulence and Biofilm Attenuates Expression of Major Toxins and Adhesins.

Hofbauer B, Vomacka J, Stahl M, Korotkov VS, Jennings MC, Wuest WM, Sieber SA. Hofbauer B, et al. Among authors: wuest wm. Biochemistry. 2018 Mar 20;57(11):1814-1820. doi: 10.1021/acs.biochem.7b01271. Epub 2018 Mar 1. Biochemistry. 2018. PMID: 29451388 Free PMC article.

6

Transcriptomic Profiling Suggests That Promysalin Alters the Metabolic Flux, Motility, and Iron Regulation in Pseudomonas putida KT2440.

Giglio KM, Keohane CE, Stodghill PV, Steele AD, Fetzer C, Sieber SA, Filiatrault MJ, Wuest WM. Giglio KM, et al. Among authors: wuest wm. ACS Infect Dis. 2018 Aug 10;4(8):1179-1187. doi: 10.1021/acsinfecdis.8b00041. Epub 2018 Jun 5. ACS Infect Dis. 2018. PMID: 29801413 Free PMC article.

7

The Natural Product Elegaphenone Potentiates Antibiotic Effects against Pseudomonas aeruginosa.

Zhao W, Cross AR, Crowe-McAuliffe C, Weigert-Munoz A, Csatary EE, Solinski AE, Krysiak J, Goldberg JB, Wilson DN, Medina E, Wuest WM, Sieber SA. Zhao W, et al. Among authors: wuest wm. Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8581-8584. doi: 10.1002/anie.201903472. Epub 2019 May 16. Angew Chem Int Ed Engl. 2019. PMID: 30969469 Free PMC article.

8

Synthetic Simplification of Carolacton Enables Chemical Genetic Studies in Streptococcus mutans.

Solinski AE, Scharnow AM, Fraboni AJ, Wuest WM. Solinski AE, et al. Among authors: wuest wm. ACS Infect Dis. 2019 Aug 9;5(8):1480-1486. doi: 10.1021/acsinfecdis.9b00213. Epub 2019 Jun 25. ACS Infect Dis. 2019. PMID: 31243986 Free PMC article.

9

Targeting S. mutans biofilms: a perspective on preventing dental caries.

Scharnow AM, Solinski AE, Wuest WM. Scharnow AM, et al. Among authors: wuest wm. Medchemcomm. 2019 Mar 19;10(7):1057-1067. doi: 10.1039/c9md00015a. eCollection 2019 Jul 1. Medchemcomm. 2019. PMID: 31391878 Free PMC article. Review.

10

A Bisphenolic Honokiol Analog Outcompetes Oral Antimicrobial Agent Cetylpyridinium Chloride via a Membrane-Associated Mechanism.

Ochoa C, Solinski AE, Nowlan M, Dekarske MM, Wuest WM, Kozlowski MC. Ochoa C, et al. Among authors: wuest wm. ACS Infect Dis. 2020 Jan 10;6(1):74-79. doi: 10.1021/acsinfecdis.9b00190. Epub 2019 Nov 12. ACS Infect Dis. 2020. PMID: 31663323 Free PMC article.

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