El Kerdawy AM - Search Results

1

Piperine solubility enhancement via DES formation: Elucidation of intermolecular interactions and impact of counterpart structure via computational and spectroscopic approaches.

Hassan SA, Zaater MA, Abdel-Rahman IM, Ibrahim EA, El Kerdawy AM, Abouelmagd SA. Hassan SA, et al. Among authors: el kerdawy am. Int J Pharm. 2024 Nov 6;667(Pt B):124893. doi: 10.1016/j.ijpharm.2024.124893. Online ahead of print. Int J Pharm. 2024. PMID: 39515673

2

Discovery of novel diaryl urea-oxindole hybrids as BRAF kinase inhibitors targeting BRAF and KRAS mutant cancers.

Ghannam IAY, El Kerdawy AM, Mounier MM, Abo-Elfadl MT, Abdel-Mohsen HT. Ghannam IAY, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 Sep 26;153:107848. doi: 10.1016/j.bioorg.2024.107848. Online ahead of print. Bioorg Chem. 2024. PMID: 39368145

3

Design, synthesis, and in silico insights of novel N'-(2-oxoindolin-3-ylidene)piperidine-4-carbohydrazide derivatives as VEGFR-2 inhibitors.

Eldehna WM, Habib YA, Mahmoud AE, Barghash MF, Elsayed ZM, Elsawi AE, Maklad RM, Rashed M, Khalil A, Hammad SF, Ali MM, El Kerdawy AM. Eldehna WM, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 Sep 18;153:107829. doi: 10.1016/j.bioorg.2024.107829. Online ahead of print. Bioorg Chem. 2024. PMID: 39317037

4

Novel benzenesulfonamides as dual VEGFR2/FGFR1 inhibitors targeting breast cancer: Design, synthesis, anticancer activity and in silico studies.

Hassan RM, Ali IH, El Kerdawy AM, Abo-Elfadl MT, Ghannam IAY. Hassan RM, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 Nov;152:107728. doi: 10.1016/j.bioorg.2024.107728. Epub 2024 Aug 17. Bioorg Chem. 2024. PMID: 39178704

5

Correlating physico-chemical properties of analytes with Hansen solubility parameters of solvents using machine learning algorithm for predicting suitable extraction solvent.

Mostafa EA, Azim MA, ElZaher AA, ElKady EF, Fouad MA, Ghazy FH, Radi EA, El Makarim Saleh MA, El Kerdawy AM. Mostafa EA, et al. Among authors: el kerdawy am. Sci Rep. 2024 Aug 13;14(1):18741. doi: 10.1038/s41598-024-68981-9. Sci Rep. 2024. PMID: 39138274 Free PMC article.

6

Design, synthesis, antineoplastic activity of new pyrazolo[3,4-d]pyrimidine derivatives as dual CDK2/GSK3β kinase inhibitors; molecular docking study, and ADME prediction.

Nemr MTM, Elshewy A, Ibrahim ML, El Kerdawy AM, Halim PA. Nemr MTM, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 Sep;150:107566. doi: 10.1016/j.bioorg.2024.107566. Epub 2024 Jun 15. Bioorg Chem. 2024. PMID: 38896936

7

Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer's disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation.

Abdo Moustafa E, Abdelrasheed Allam H, Fouad MA, El Kerdawy AM, Nasser Eid El-Sayed N, Wagner C, Abdel-Aziz HA, Abdel Fattah Ezzat M. Abdo Moustafa E, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 May;146:107324. doi: 10.1016/j.bioorg.2024.107324. Epub 2024 Mar 30. Bioorg Chem. 2024. PMID: 38569322

8

In Silico and In Vitro Screening of Some Pregnane Glycosides Isolated from Certain Caralluma Species as SARS-COV-2 Main Protease Inhibitors.

Abdel-Sattar E, Kutkat O, El-Shiekh RA, El-Ashrey MK, El Kerdawy AM. Abdel-Sattar E, et al. Among authors: el kerdawy am. Chem Biodivers. 2024 Apr;21(4):e202301786. doi: 10.1002/cbdv.202301786. Epub 2024 Mar 11. Chem Biodivers. 2024. PMID: 38466126

9

Novel thiazolidin-4-one benzenesulfonamide hybrids as PPARγ agonists: Design, synthesis and in vivo anti-diabetic evaluation.

Ali IH, Hassan RM, El Kerdawy AM, Abo-Elfadl MT, Abdallah HMI, Sciandra F, Ghannam IAY. Ali IH, et al. Among authors: el kerdawy am. Eur J Med Chem. 2024 Apr 5;269:116279. doi: 10.1016/j.ejmech.2024.116279. Epub 2024 Feb 29. Eur J Med Chem. 2024. PMID: 38460271

10

Benzimidazole-oxindole hybrids as multi-kinase inhibitors targeting melanoma.

Allam RM, El Kerdawy AM, Gouda AE, Ahmed KA, Abdel-Mohsen HT. Allam RM, et al. Among authors: el kerdawy am. Bioorg Chem. 2024 May;146:107243. doi: 10.1016/j.bioorg.2024.107243. Epub 2024 Feb 26. Bioorg Chem. 2024. PMID: 38457953

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