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Fish-hunting cone snail disrupts prey's glucose homeostasis with weaponized mimetics of somatostatin and insulin.
Yeung HY, Ramiro IBL, Andersen DB, Koch TL, Hamilton A, Bjørn-Yoshimoto WE, Espino S, Vakhrushev SY, Pedersen KB, de Haan N, Hipgrave Ederveen AL, Olivera BM, Knudsen JG, Bräuner-Osborne H, Schjoldager KT, Holst JJ, Safavi-Hemami H. Yeung HY, et al. Among authors: olivera bm. Nat Commun. 2024 Aug 20;15(1):6408. doi: 10.1038/s41467-024-50470-2. Nat Commun. 2024. PMID: 39164229 Free PMC article.
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3.
Hackney CM, Flórez Salcedo P, Mueller E, Koch TL, Kjelgaard LD, Watkins M, Zachariassen LG, Tuelung PS, McArthur JR, Adams DJ, Kristensen AS, Olivera B, Finol-Urdaneta RK, Safavi-Hemami H, Morth JP, Ellgaard L. Hackney CM, et al. PLoS Biol. 2023 Aug 3;21(8):e3002217. doi: 10.1371/journal.pbio.3002217. eCollection 2023 Aug. PLoS Biol. 2023. PMID: 37535677 Free PMC article.
A toxin-based approach to neuropeptide and peptide hormone discovery.
Koch TL, Torres JP, Baskin RP, Salcedo PF, Chase K, Olivera BM, Safavi-Hemami H. Koch TL, et al. Among authors: olivera bm. Front Mol Neurosci. 2023 Aug 31;16:1176662. doi: 10.3389/fnmol.2023.1176662. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37720554 Free PMC article.
Prey Shifts Drive Venom Evolution in Cone Snails.
Koch TL, Robinson SD, Salcedo PF, Chase K, Biggs J, Fedosov AE, Yandell M, Olivera BM, Safavi-Hemami H. Koch TL, et al. Among authors: olivera bm. Mol Biol Evol. 2024 Aug 2;41(8):msae120. doi: 10.1093/molbev/msae120. Mol Biol Evol. 2024. PMID: 38935574 Free PMC article.
CYP1B1-derived epoxides modulate the TRPA1 channel in chronic pain.
Sun L, Zhang J, Niu C, Deering-Rice CE, Hughen RW, Lamb JG, Rose K, Chase KM, Almestica-Roberts M, Walter M, Schmidt EW, Light AR, Olivera BM, Reilly CA. Sun L, et al. Among authors: olivera bm. Acta Pharm Sin B. 2023 Jan;13(1):68-81. doi: 10.1016/j.apsb.2022.09.007. Epub 2022 Sep 14. Acta Pharm Sin B. 2023. PMID: 36815047 Free PMC article.
425 results