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Page 1
The nuclear export protein XPO1 provides a peptide ligand for natural killer cells.
Blunt MD, Fisher H, Schittenhelm RB, Mbiribindi B, Fulton R, Khan S, Espana-Serrano L, Graham LV, Bastidas-Legarda L, Burns D, Khakoo SMS, Mansour S, Essex JW, Ayala R, Das J, Purcell AW, Khakoo SI. Blunt MD, et al. Among authors: essex jw. Sci Adv. 2024 Aug 23;10(34):eado6566. doi: 10.1126/sciadv.ado6566. Epub 2024 Aug 23. Sci Adv. 2024. PMID: 39178254 Free PMC article.
Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10.
Ahmed M, Mackenzie J, Tezera L, Krause R, Truebody B, Garay-Baquero D, Vallejo A, Govender K, Adamson J, Fisher H, Essex JW, Mansour S, Elkington P, Steyn AJC, Leslie A. Ahmed M, et al. Among authors: essex jw. Commun Biol. 2022 Dec 1;5(1):1317. doi: 10.1038/s42003-022-04265-0. Commun Biol. 2022. PMID: 36456824 Free PMC article.
CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains.
Chancellor A, Tocheva AS, Cave-Ayland C, Tezera L, White A, Al Dulayymi JR, Bridgeman JS, Tews I, Wilson S, Lissin NM, Tebruegge M, Marshall B, Sharpe S, Elliott T, Skylaris CK, Essex JW, Baird MS, Gadola S, Elkington P, Mansour S. Chancellor A, et al. Among authors: essex jw. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10956-E10964. doi: 10.1073/pnas.1708252114. Epub 2017 Nov 20. Proc Natl Acad Sci U S A. 2017. PMID: 29158404 Free PMC article.
Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.
Mansour S, Tocheva AS, Cave-Ayland C, Machelett MM, Sander B, Lissin NM, Molloy PE, Baird MS, Stübs G, Schröder NW, Schumann RR, Rademann J, Postle AD, Jakobsen BK, Marshall BG, Gosain R, Elkington PT, Elliott T, Skylaris CK, Essex JW, Tews I, Gadola SD. Mansour S, et al. Among authors: essex jw. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1266-75. doi: 10.1073/pnas.1519246113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884207 Free PMC article.
Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility.
Orr CM, Fisher H, Yu X, Chan CH, Gao Y, Duriez PJ, Booth SG, Elliott I, Inzhelevskaya T, Mockridge I, Penfold CA, Wagner A, Glennie MJ, White AL, Essex JW, Pearson AR, Cragg MS, Tews I. Orr CM, et al. Among authors: essex jw. Sci Immunol. 2022 Jul 15;7(73):eabm3723. doi: 10.1126/sciimmunol.abm3723. Epub 2022 Jul 8. Sci Immunol. 2022. PMID: 35857577
A review of protein-small molecule docking methods.
Taylor RD, Jewsbury PJ, Essex JW. Taylor RD, et al. Among authors: essex jw. J Comput Aided Mol Des. 2002 Mar;16(3):151-66. doi: 10.1023/a:1020155510718. J Comput Aided Mol Des. 2002. PMID: 12363215 Review.
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